A dendrified bactericidal microsphere and its preparation method and application
A microsphere and tree-shaped technology, applied in the field of novel tree-shaped bactericidal microspheres and their preparation, can solve the problems of poor peeling and washing effects, high transportation and storage costs, toxic by-products, etc., so as to avoid secondary pollution, overcome the Residual water body, the effect of improving the bactericidal power
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Embodiment 1
[0045] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:
[0046] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:3, feeds N 2 protection, stirring the reaction at 90°C for 10h, and filtering off the reacted G0.5. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;
[0047] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise ...
Embodiment 2
[0054] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:
[0055] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:4, feeds N 2 Protected, stirred and reacted at 100°C for 11h, and the reacted G0.5 was filtered off. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;
[0056] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise...
Embodiment 3
[0063] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:
[0064] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:5, feeds N 2protection, stirring the reaction at 110°C for 12h, and filtering off the reacted G0.5. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;
[0065] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise ...
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