Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A composition and drug technology, applied in the field of medicine, can solve the problem that the recurrence of patients is not ideally controlled
Inactive Publication Date: 2017-08-18
牛永友
View PDF1 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
The traditional method of treating asthma is the use of glucocorticoids and bronchodilators. However, the recurrence of patients is still not ideally controlled. Therefore, it is urgent to develop effective therapeutic drugs
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
experiment example 1
[0021] The characterization of experimental example 1 medicine of the present invention
[0024] Experimental example 2 the effect of medicine treatment asthma of the present invention
[0025] Grouping and Model Building
[0026] All mice were divided into normal control group, model control group, drug group of the present invention and dexamethasone group according to the random number table method, with 10 mice in each group. Except for the normal group, 0.2 mL of the sensitizing solution was injected intraperitoneally on the 1st and 14th day for sensitization, and on the 14th, 25th, 26th, and 27th day, after intraperitoneal injection of pentobarbital sodium for anesthesia, 0.05 mL of the stimulating solution was given nasal drops excitation. On the 28th~41 days, the model control group gave 0.9% sodium chloride solution 0.5mL for intragastric administration, the drug group of the present invention gave embodiment 1 medicine 10mg / kg for intragastric administration, and the dexamethasone group intraperitoneally injected dexamethasone 0.5mL (1mg / kg). kg). The ...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
In order to alleviate the airway inflammatory response of asthma patients, the invention discloses a pharmaceutical composition for treating asthma. The pharmaceutical composition uses the compound with the innovative structure of the following formula as an active ingredient: The medicament of the invention has good effects in alleviating airway inflammatory response of asthma patients, inhibiting asthma and improving lung function, and is expected to be developed into a medicament for treating asthma in clinical application.
Description
technical field [0001] The invention relates to the field of medicine, in particular, the invention relates to a pharmaceutical composition for treating asthma and the application of the compound in preparing medicine for treating asthma. Background technique [0002] Asthma is a chronic inflammatory disease of the airways in which many cells in the innate and acquired immune systems, together with epithelial cells, cause bronchial hyperresponsiveness, mucus overproduction, airway inflammatory cell infiltration, airway remodeling, and airway narrowing . The traditional method of treating asthma is the use of glucocorticoids and bronchodilators. However, the recurrence of patients is still not well controlled. Therefore, it is urgent to develop effective therapeutic drugs. Contents of the invention [0003] The object of the present invention is to provide a pharmaceutical composition for treating asthma. [0004] In order to realize the purpose of the present invention, ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.