Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of traditional Chinese medicine composition and its application in preparing medicine for treating pulmonary fibrosis disease

A technology of pulmonary fibrosis and composition, which is applied in the field of preparation of drugs for the treatment of pulmonary fibrosis, can solve the problems that drugs are difficult to achieve effective treatment, etc.

Active Publication Date: 2021-10-26
BINZHOU MEDICAL COLLEGE
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pathogenesis of pulmonary fibrosis is complexly regulated by multiple factors, and it is difficult to achieve effective treatment with a single-target drug. Therefore, people began to pay more attention to multi-component, multi-target traditional Chinese medicine.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of traditional Chinese medicine composition and its application in preparing medicine for treating pulmonary fibrosis disease
  • A kind of traditional Chinese medicine composition and its application in preparing medicine for treating pulmonary fibrosis disease
  • A kind of traditional Chinese medicine composition and its application in preparing medicine for treating pulmonary fibrosis disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1. The preparation of Chinese medicine composition oral liquid

[0029] Take 300g of Astragalus, 200g of Codonopsis, 100g of Ophiopogon japonicus, 100g of Schisandra chinensis, 50g of Panax notoginseng, 100g of Zhebei, 100g of Anemarrhena, 50g of roasted licorice, the above eight flavors, add 20 liters of water, decoct twice, 2 hours each time, combine The decoction is concentrated to 10 liters, left to stand overnight, filtered, and the filtrate is added with 5% white granulated sugar and 0.01% potassium sorbate, filled and sterilized to obtain the product. Each bottle is equivalent to 10g of raw medicinal materials.

Embodiment 2

[0030] Embodiment 2. The preparation of Chinese medicine composition ointment

[0031] Take 300g Sun-roasted Astragalus, 180g Codonopsis, 120g Ophiopogon japonicus, 90g Southern Schisandra, 60g Panax notoginseng, 60g Zhebei, 60g Anemarrhena, 30g Zhigancao, the above eight flavors, add 20 liters of water, decoct twice, 2 hours each time, Combine the decoction liquid, concentrate to 10 liters, stand overnight, filter, and further concentrate the filtrate to a clear paste (density 1.1-1.5), add 5% white sugar and 0.01% potassium sorbate, fill and sterilize, to obtain . Each ml of extract is equivalent to 1g of the original medicinal material.

Embodiment 3

[0032] Embodiment 3. The preparation of Chinese medicine composition granule

[0033] Take 250g Astragalus, 200g Codonopsis, 150g Ophiopogon japonicus, 100g Southern Schisandra, 100g Panax notoginseng, 100g Chuanbei, 100g Anemarrhena, 50g roasted licorice, the above eight flavors, add 20 liters of water, decoct twice, 2 hours each time, combine After the decoction is concentrated to a clear paste, powdered sugar is added as an auxiliary material at a ratio of 1:1, mixed evenly, granulated, dried and packaged to obtain the product. Each bag is equivalent to 10g of raw medicinal materials.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the composition and preparation method of a traditional Chinese medicine composition and its application in the preparation of anti-pulmonary fibrosis medicine. The composition is composed of astragalus, codonopsis radix, radices japonicus, schisandra chinensis, panax notoginseng, zhebei, anemarrhena anemarrhena and licorice. The composition can regulate the expression of short-chain non-coding RNAs (miRNAs) and long-chain non-coding RNAs (lncRNA), has the effect of protecting alveolar epithelial cells, interfering with the activity of myofibroblasts, and then inhibiting the process of pulmonary fibrosis, therefore The composition is expected to be well applied in the preparation of medicines for treating pulmonary fibrosis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition and its application in preparing medicine for treating pulmonary fibrosis. Background technique [0002] Pulmonary fibrosis (PF) is a group of pulmonary interstitial diseases of unknown etiology, with progressively aggravated dyspnea as the most prominent clinical manifestation, and the main pathological features are alveolar epithelial cell damage, fibroblast activation, fibroblast Foci formation and excessive deposition of extracellular matrix eventually lead to abnormal remodeling of lung tissue architecture. The current treatment drugs are mainly corticosteroids, immunosuppressants, anti-inflammatory drugs, and cytotoxic drugs, but most patients are not sensitive to drugs, the disease progresses rapidly, and the mortality rate is high. Treatment is still an international problem. In the study of anti-pulmonary fibrosis ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P11/00
CPCA61K9/0053A61K9/06A61K9/08A61K9/1623A61K9/2018A61K9/2031A61K9/4858A61K36/258A61K36/344A61K36/481A61K36/484A61K36/57A61K36/79A61K36/8964A61K36/8966A61K36/8968A61K47/26A61K2300/00
Inventor 吕长俊刘玉霞刘博宋晓冬王友磊张瑾锦曲桂武
Owner BINZHOU MEDICAL COLLEGE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com