Pharmaceutical composition for treating neurodermatitis and preparation method of pharmaceutical composition

A composition and neurological technology, applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the lack of experimental research such as pharmacology and toxicology, no random control in literature, and irregular naming of external preparations, etc. question

Inactive Publication Date: 2017-06-13
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The etiology of neurodermatitis in Western medicine is not very clear, and it is speculated that it is related to the imbalance of nerve regulation function, while traditional Chinese medicine acupuncture and Chinese herbal medicine have the advantages of definite clinical curative effect, quick onset, and less adverse reactions, which can quickly relieve local symptoms and promote local dermatitis. However, acupuncture and Chinese herbal medicine also have their shortcomings: such as irregular naming of external preparations, immature preparation technology, and no unified treatment standard for preparations; some literatures have no randomized control, and lack of pharmacological and toxicological experimental studies, etc. problem; and the mechanism of Chinese medicine treatment of neurodermatitis is not yet very clear

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition for the treatment of neurodermatitis and preparation method thereof

[0039] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating neurodermatitis are: ephedrine 30g, 470g kaleidoscope 327g, 9g of inulatin, 5g of telegalic acid, and 1.5g of corosolic acid;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take ephedrine, kale, prolactin, inulalide, telegalic acid, and corosolic acid, mix them evenly, and use ethanol with a concentration of 35% by weight as a solvent, at 38.5°C Warm immersion extraction, the number of extractions is 12 times, each extraction time is 1.5 hours, and the amount of solvent each time is 21 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.13, filter, the liquid medicine passes through the H-10 macroporous a...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for the treatment of neurodermatitis and preparation method thereof

[0045] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating neurodermatitis are: ephedrine 25g, 480g kaleidoscope 326g, inulatin 10g, telegalic acid 4g, and corosolic acid 2g;

[0046] Preparation:

[0047] (1) According to the ratio of raw materials, take ephedrine, kale, prolactin, inulalide, telegalic acid, and corosolic acid, mix them evenly, and use ethanol with a concentration of 35% by weight as a solvent, at 38.5°C Warm immersion extraction, the number of extractions is 12 times, each extraction time is 1.5 hours, and the amount of solvent each time is 21 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.13, filter, the liquid medicine passes through the H-10 macroporous adsorption ...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition for the treatment of neurodermatitis and preparation method thereof

[0051] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating neurodermatitis are: ephedrine 35g, 460g of kaleidopsis, 328g of prolactin, 8g of inulatin, 6g of telegalic acid, and 1g of corosolic acid;

[0052] Preparation:

[0053] (1) According to the ratio of raw materials, take ephedrine, kale, prolactin, inulalide, telegalic acid, and corosolic acid, mix them evenly, and use ethanol with a concentration of 35% by weight as a solvent, at 38.5°C Warm immersion extraction, the number of extractions is 12 times, each extraction time is 1.5 hours, and the amount of solvent each time is 21 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.13, filter, the liquid medicine passes through the H-10...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating neurodermatitis and a preparation method thereof. The pharmaceutical composition of the invention is composed of ephedrine, japonica, prolactin, inulalide, telegalic acid, and corosolic acid It is a raw material medicine prepared in proportion, and can be made into various dosage forms according to conventional preparation techniques, and has remarkable curative effect in treating neurodermatitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating neurodermatitis and a preparation method thereof. Background technique [0002] Neurodermatitis, also known as lichen simplex chronicus, is a common and frequently occurring chronic skin disease characterized by lichenification of the skin and severe itching, which is equivalent to psoriasis or sores in Chinese medicine. The etiology of neurodermatitis is not very clear yet, but it has a clear relationship with nerve and mental factors. Therefore, Western medicine treatment mainly focuses on symptomatic relief of pruritus, oral antihistamines, sedative and hypnotics for severe cases, and external use of glucocorticoids Although it can temporarily relieve the condition, it is easy to relapse after stopping the drug, and the side effects are relatively large after repeated application. [0003] The etiolog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/27A61P17/00A61K31/421A61K36/185A61K31/365A61K31/58A61K31/56
CPCA61K31/421A61K31/365A61K31/56A61K31/58A61K36/185A61K36/27A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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