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Application of triglyceride as marker in preparation of melancholia diagnosis or treatment effect evaluation kit and kit

A diagnostic kit and triglyceride technology, which is applied in disease diagnosis, biological testing, biomaterial analysis, etc., can solve the problems of incompletely clear etiology of depression and lack of biomarkers

Active Publication Date: 2017-05-31
苏州市广济医院
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the etiology of depression is still not completely clear, and the diagnosis of depression is still based on clinical manifestations and scales. At present, there is still a lack of biomarkers related to the diagnosis of depression. objective indicators

Method used

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  • Application of triglyceride as marker in preparation of melancholia diagnosis or treatment effect evaluation kit and kit
  • Application of triglyceride as marker in preparation of melancholia diagnosis or treatment effect evaluation kit and kit
  • Application of triglyceride as marker in preparation of melancholia diagnosis or treatment effect evaluation kit and kit

Examples

Experimental program
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Effect test

Embodiment

[0041] In this example, the correlation between serum triglyceride and severe depression is verified by taking healthy people as controls and patients with severe depression as objects.

[0042] 1. Subjects:

[0043] 115 outpatients and inpatients with severe depression from the Guangji Hospital Affiliated to Soochow University. The diagnosis of each patient was made by two senior psychiatrists, and the diagnostic criteria were based on DSM-IV-TR.

[0044] Exclusion criteria include: 1) main or comorbid diagnosis according to DSM-IV: organic psychosis, dementia, schizophrenia, delusional (mental) disorder or schizoaffective disorder, substance abuse; 2) pregnancy; 3) possible History of intellectual deficits affecting cognition.

[0045] 119 healthy controls were from the physical examination center of the hospital. The healthy control group used the Simple Depression Rating Scale (SDS), and the score less than 50 was included in the group.

[0046] All subjects were Chinese...

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Abstract

The invention discloses application of triglyceride as a marker in preparation of a melancholia diagnosis or treatment effect evaluation kit and the kit and belongs to the technical field of melancholia diagnosis. According to the application and the kit, research results find that the triglyceride is closely related to melancholia, the condition that the triglyceride is applied to the field related to preparation of melancholia diagnosis kits as the marker is provided for the first time, the defect of a melancholia diagnosis process that used indicators are not objective in diagnosis at present is overcome, and then, a bran-new and more accurate objective indicator is provided for the diagnosis of late melancholia, particularly major depressive disorder, more particularly major depressive disorders with cognitive function lowered or injured characteristics or drug treatment effect evaluation.

Description

technical field [0001] The invention relates to the technical field of depression diagnosis, in particular to the application of triglyceride as a marker in the preparation of a depression diagnosis or curative effect evaluation kit and the kit. Background technique [0002] Depression is a mental illness with persistent low mood as the main symptom caused by multiple reasons, and its clinical manifestations are diverse. Depression is a common psychiatric disease, and the World Health Organization predicts that by 2020, depression will become the second most common disease. [0003] The pathogenesis of depression is complex, involving multi-system and multi-link dysfunction, which can be manifested as abnormal dynamic balance of various biochemical substances. Unfortunately, the etiology of depression is still not completely clear, and the diagnosis of depression is still based on clinical manifestations and scales. At present, there is still a lack of biomarkers related to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/50
CPCG01N33/50G01N2800/304
Inventor 惠李殷光中丁智慧邵天男杜向东满丽娟陈洁朱宏亮李佳张兰兰
Owner 苏州市广济医院
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