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Carbon quantum dot/nano-silver alginate dressing and preparation method and application thereof

A technology of carbon quantum dots and silver alginate, which is applied in the field of carbon quantum dots/nano silver alginate dressings and its preparation, can solve the problems of chronic wound treatment with few carbon quantum dots, achieve fast and effective detection methods, increase Effect of physical crosslinking reaction, good mechanical properties and comfort

Active Publication Date: 2017-05-31
广州锐晟科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few studies on the application of carbon quantum dots in the treatment of chronic wounds

Method used

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  • Carbon quantum dot/nano-silver alginate dressing and preparation method and application thereof
  • Carbon quantum dot/nano-silver alginate dressing and preparation method and application thereof
  • Carbon quantum dot/nano-silver alginate dressing and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method of carbon quantum dot / nanometer silver alginate dressing, its specific preparation steps are:

[0029] (1) Dissolve 1.0 g of silver nitrate solid particles in 1 L of deionized water to form a silver nitrate solution, and add 10.0 g of polyethylene glycol 400 and 3.0 g of sodium citrate in sequence, stir to dissolve, and then add 4.0 g of Anticorrosion, 5.0 g carbon quantum dots, react at 30°C for 0.5 h, centrifuge after the reaction, centrifuge at 5000 rpm for 10 min, wash with ethanol and deionized water in sequence, repeat 3 times, and finally freeze Dry for 24 h to obtain a carbon quantum dot / nano-silver composite; the size of the carbon quantum dot is less than 5 nm, and the thickness is 1.05 nm; the size of the nano-silver in the carbon quantum dot / nano-silver composite is 15 nm;

[0030](2) Weigh 10.0 g of sodium alginate and dissolve it in 500 mL of deionized water to prepare a sodium alginate solution; add 0.1 g of carbon quantum dots / nano-s...

Embodiment 2

[0033] A preparation method of carbon quantum dot / nanometer silver alginate dressing, its specific preparation steps are:

[0034] (1) Dissolve 1.0 g of silver nitrate solid particles in 1 L of deionized water to form a silver nitrate solution, and add 15.0 g of polyethylene glycol 400 and 8.0 g of sodium citrate in turn, stir to dissolve, and then add 8.0 g of Anticorrosion, 10.0 g carbon quantum dots, react at 40°C for 45 min, centrifuge after the reaction, centrifuge at 5000 rpm for 10 min, wash with ethanol and deionized water in sequence, repeat 3 times, and finally freeze Dry for 24 h to obtain a carbon quantum dot / nano-silver composite material; the size of the carbon quantum dot is less than 5 nm, and the thickness is 1.05 nm; the nano-silver size in the carbon quantum dot / nano-silver composite material is 30 nm;

[0035] (2) Weigh 10.0 g of sodium alginate and dissolve it in 500 mL of deionized water to prepare a sodium alginate solution; add 0.5 g of carbon quantum d...

Embodiment 3

[0038] A preparation method of carbon quantum dot / nanometer silver alginate dressing, its specific preparation steps are:

[0039] (1) Dissolve 1.0 g of silver nitrate solid particles in 1 L of deionized water to form a silver nitrate solution, and add 20.0 g of polyethylene glycol 400 and 12.0 g of sodium citrate in turn, stir to dissolve, and then add 12.0 g of Anticorrosion, 15.0 g carbon quantum dots, react at 50°C for 1 h, centrifuge after the reaction, centrifuge at 5000 rpm for 10 min, wash with ethanol and deionized water in sequence, repeat 3 times, and finally freeze Dry for 24 h to obtain a carbon quantum dot / nano-silver composite; the size of the carbon quantum dot is less than 5 nm, and the thickness is 1.05 nm; the size of the nano-silver in the carbon quantum dot / nano-silver composite is 50 nm;

[0040] (2) Weigh 10.0 g of sodium alginate and dissolve it in 500 mL of deionized water to prepare a sodium alginate solution; add 1.0 g of carbon quantum dots / nano-sil...

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Abstract

The invention belongs to the technical field of medical dressing, and discloses a carbon quantum dot / nano-silver alginate dressing and a preparation method and application thereof. A carbon quantum dot / nano-silver composite material is prepared from silver nitrate, polyethylene glycol 400, sodium citrate, ascorbic acid and carbon quantum dots; and the carbon quantum dot / nano-silver composite material is added to a sodium alginate solution to prepare the carbon quantum dot / nano-silver alginate dressing through an electrostatic spinning technology and a non-woven technology. According to the dressing prepared by the technology, the mechanical property of the alginate dressing can be significantly improved; meanwhile, the dressing has an excellent fluorescent display tracking function; the migration change and the accumulation condition of silver ions in a body can be effectively inspected; and a fast and effective detection method is provided for clinical supervision of the silver ions.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, and in particular relates to a carbon quantum dot / nano silver alginate dressing and a preparation method and application thereof. Background technique [0002] Alginate is a polysaccharide extracted from brown algae kelp or sargassum, and is a natural three-dimensional network polymer material. It has excellent properties such as non-toxic, non-irritating, high hygroscopicity, and biocompatibility, and is widely used in drug delivery systems and pharmaceutical fields. After the sheet-shaped alginate dressing absorbs the wound exudate, it forms a gel. During the gel formation process, the calcium ions in the alginate dressing exchange with the sodium ions in the exudate, destroying the three-dimensional network of alginate. Shaped structure, resulting in decreased mechanical properties of alginate dressing after fluid absorption, easy to break. [0003] Postoperative infection is one o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/46A61L15/28A61K49/00
CPCA61K49/0017A61K49/0067A61L15/28A61L15/42A61L15/46A61L2300/104A61L2300/404A61L2300/602C08L5/04
Inventor 卢亢陈锦涛李婷
Owner 广州锐晟科技有限公司
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