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Drug combination for treating rheumatism arthritis and preparation method thereof

A technology for arthritis and rheumatoid arthritis, which is applied in the field of pharmaceutical compositions for the treatment of rheumatoid arthritis and its preparation, and can solve problems such as the lack of formulation studies and pharmacological mechanisms of action, and the inability to provide clinical references, etc.

Active Publication Date: 2017-03-29
湖北领康中药材有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a pharmaceutical composition for treating rheumatoid arthritis and its preparation method, aiming to solve the problem that there is a lack of research on its preparation molding and pharmacological mechanism of action, and it cannot better provide clinical information. The question of reference

Method used

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  • Drug combination for treating rheumatism arthritis and preparation method thereof
  • Drug combination for treating rheumatism arthritis and preparation method thereof
  • Drug combination for treating rheumatism arthritis and preparation method thereof

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preparation example Construction

[0028] Such as figure 1 As shown, the preparation method of the pharmaceutical composition for the treatment of rheumatoid arthritis provided by the embodiments of the present invention comprises the following steps:

[0029] S101: Weigh 10-30 parts of Bamboo Ginseng, 10-30 parts of Astilbe, 10-30 parts of Aesculus, 20-60 parts of Kidnapper Medicine, 15-45 parts of Sanbai stick, tiger Prick 15 to 45 parts and pass through a 160-mesh sieve to obtain the raw material drug;

[0030] S102: uniformly mix the raw materials of bamboo ginseng, astilbee, aescin, kidnapper, three hundred rods, and tiger thorn to obtain the product;

[0031] S103: Mix the raw materials of bamboo ginseng, astilbee, aescin, kidnapping medicine, three hundred rods, and tiger thorn, add water 6 to 10 times the amount of the raw materials, heat and reflux for 1.5 hours, and extract for 2 to 10 times. 3 times, filtered, combined filtrates, concentrated under reduced pressure to obtain extract, dried and pulv...

Embodiment 1

[0034] Embodiment 1: A Tujia medicinal composition for treating rheumatoid arthritis, made from the following raw materials:

[0035] Weigh and pulverize respectively the crude drugs that have passed through a 160-mesh sieve: 30g of Panax ginseng, 30g of Astilbe, 30g of Aescin, 20g of Kidnapper medicine, 15g of Sanbai stick, 15g of tiger thorn, and mix well to obtain.

Embodiment 2

[0036] Embodiment 2: A Tujia medicinal composition for treating rheumatoid arthritis, made from the following raw materials:

[0037] Weigh and pulverize respectively the raw materials of the 160-mesh sieve: 20g of Panax ginseng, 20g of Astilbe, 20g of Aescin, 30g of Kidnapper medicine, 30g of Sanbai stick, 30g of tiger thorn, and mix evenly to obtain.

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Abstract

The invention discloses a drug combination for treating rheumatism arthritis and a preparation method thereof. The drug combination for treating rheumatism arthritis comprises, by weight, 10-30 parts of panax japonicas, 10-30 parts of astilbe chinensis, 10-30 parts of paris polyphylla, 20-60 parts of clematis henryi oliv, 15-45 parts of toddalia asiatualam and 15-45 parts of Indian damnacanthus herbs. The preparation method includes the steps that raw medicines are weighed separately and subjected to 160-mesh sieving, and the raw medicines are obtained; and the raw medicines including the panax japonicas, the astilbe chinensis, the paris polyphylla, the clematis henryi oliv, the astilbe chinensis and the Indian damnacanthus herbs are mixed evenly, and the drug combination for treating rheumatism arthritis is obtained. The drug combination for treating rheumatism arthritis has the effects of dispelling wind, eliminating dampness, dispersing blood stasis, relieving pain, promoting qi to activate blood, warming and activating meridian, and achieving nourishing and strengthening, has significant clinical effects and has no obvious toxic or side effects. The drug combination for treating rheumatism arthritis has a significant therapeutic effect on arthritis induced by a complete Freund's adjuvant, has good anti-inflammatory and analgesic effects, achieves the pharmacological function significantly superior to that of a single medicinal material and other compatible combinations, plays a synergetic interaction and has low toxic and side effects.

Description

technical field [0001] The invention belongs to the technical field of treating rheumatoid arthritis, and in particular relates to a pharmaceutical composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (Rheumatism Arthritis, RA) is a chronic, systemic autoimmune disease characterized by joint synovitis, with chronic, symmetrical, polysynovial arthritis and extra-articular lesions as the main clinical manifestations , occurs in small joints such as hands, wrists, and feet, and its etiology may be related to differences in geography, endocrine, nutrition, occupation, psychology, and social environment, bacterial and viral infections, and genetic factors. In the early stage, the joints are red, swollen, hot, painful, and dysfunctional, and in the late stage, the joints may be stiff and deformed in varying degrees, accompanied by atrophy of bones and skeletal muscles, which is very easy to cause disabil...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/86A61K9/48A61K9/20A61K9/16A61K9/14A61P29/00A61P19/02
CPCA61K9/141A61K9/1605A61K9/2004A61K9/4841A61K36/11A61K36/185A61K36/258A61K36/716A61K36/74A61K36/86A61K36/896A61K2236/331A61K2236/39A61K2300/00
Inventor 涂星张燕文德鉴胡泽华王利胜郜红利田春漫袁德培向阳袁林
Owner 湖北领康中药材有限公司
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