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Bionic perfusion method for branch blood vessel model for liver perfusion

A blood vessel model and liver blood vessel technology, which is applied in the field of the entity model of secondary liver blood vessels to achieve accurate blood vessel dynamics parameters and ideal cleaning effect.

Inactive Publication Date: 2017-02-15
TIANJIN UNIVERSITY OF TECHNOLOGY
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

These studies mainly revolve around the modeling of straight blood vessels and corresponding mechanical analysis, but there are few studies on the dynamic analysis of branch blood vessels using perfusate

Method used

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  • Bionic perfusion method for branch blood vessel model for liver perfusion
  • Bionic perfusion method for branch blood vessel model for liver perfusion
  • Bionic perfusion method for branch blood vessel model for liver perfusion

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Embodiment Construction

[0021] In order to make the content of the present invention more easily understood, the present invention will be described in further detail below in conjunction with the accompanying drawings according to specific embodiments of the present invention. It is carried out in the form of non-smooth blood vessel perfusion simulation through finite element analysis software.

[0022] The overall idea of ​​the invention to solve its technology is:

[0023] (1) Before liver transplantation, during the cleaning (perfusion) process of the liver donor, first determine the specific size and parameters of the branch vessels according to the medical image data; secondly, construct liver vessel models with different branch angles; According to the medical data, the angiodynamic parameters for evaluating the quality of vascular perfusion are determined, indicating the feasibility of branch vessel perfusion. (2) The specific dimensions and parameters of the branch vessels can be measured a...

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Abstract

The invention discloses a bionic perfusion method for a branch blood vessel model for liver perfusion. A mathematical simulation method is used for simulating a donor perfusion cleaning process before liver transplantation, and comprises the following steps: 1, determining specific dimensions and parameters of liver blood vessels at different branch angles according to medical image data; 2, constructing liver blood vessel models at different branch angles; 3, introducing intermittent double pulsating flow into the blood vessels, observing blood vessel kinetic phenomena generated in a perfusion process through medical measures, and determining blood vessel kinetic parameters, which are used for evaluating the blood vessel perfusion quality, according to the medical data; and finally, analyzing and comparing kinetic characteristic results obtained by perfusion of the branch blood vessels at different branch angles, and indicating that when the branch angles are about 60 degrees, a relatively good kinetic characteristic is realized. Therefore, a certain theoretical foundation is supplied to a mounting angle of a blood vessel stent of medical clinical application to relieving of hemadostenosis jam.

Description

technical field [0001] The invention relates to a branch blood vessel model for liver perfusion, in particular to a solid model of a secondary liver blood vessel including a branch node, which simulates the perfusion and cleaning process of the perfusion fluid before liver transplantation. Background technique [0002] The mortality rate induced by liver disease is very high in both developed and underdeveloped areas at home and abroad. Liver transplantation is currently the only effective means of treating end-stage liver disease. The quality of the liver donor is one of the key links affecting the success rate of liver transplantation. Cleaning (perfusion) of the liver donor before operation is a necessary medical procedure. Therefore, the quality of vascular perfusion directly affects the success of the operation. Many scholars at home and abroad have studied the process of vascular perfusion, analyzed the different phenomena and final effects of different vascular perfu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B34/10
Inventor 刘军田兰兰王松丽葛为民陈建恩王肖峰
Owner TIANJIN UNIVERSITY OF TECHNOLOGY
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