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A high-definition fast magnetic resonance imaging method based on radio frequency pulse multi-mode weighting

A technology of magnetic resonance imaging and radio frequency pulse, which is applied in the direction of using nuclear magnetic resonance imaging system for measurement, magnetic resonance measurement, measurement of magnetic variables, etc., to achieve the effect of reducing the number of excitations, reducing image artifacts, and shortening imaging time

Active Publication Date: 2018-12-25
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current K-space excitation method of CS-MRI is fixed-angle excitation or variable-angle excitation. In addition to the introduction of under-sampling artifacts, it still faces the problems caused by full-sampling fixed-angle excitation or variable-angle excitation imaging.

Method used

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  • A high-definition fast magnetic resonance imaging method based on radio frequency pulse multi-mode weighting
  • A high-definition fast magnetic resonance imaging method based on radio frequency pulse multi-mode weighting
  • A high-definition fast magnetic resonance imaging method based on radio frequency pulse multi-mode weighting

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Embodiment 1

[0044] A high-definition fast magnetic resonance imaging method based on radio frequency pulse multimode weighting disclosed by the present invention comprises the following steps:

[0045] Step 1. Collect hyperpolarized gas and use the hyperpolarized gas as a contrast agent. The hyperpolarized gas includes 3He or 129Xe or 131Xe or 83Kr, etc. The collected hyperpolarized gas is stored as a gas or as a solid, wherein the solid is sublimated to a gas upon use.

[0046] Step 2: Perform proton MR positioning imaging on the imaging object to obtain position information of the imaging object. The imaging object includes liquid or solid or biological tissue or animal or human etc. The sequence used for proton MR positioning is the FLASH sequence.

[0047] Step 3. Use radio frequency pulses to carry out multi-mode weighting on different areas of the original K-space of the imaging object, and use the pulse gradient field to perform 2-dimensional or 3-dimensional encoding on the ima...

Embodiment 2

[0059] In this example,

[0060] The hyperpolarized gas is 129Xe.

[0061] The imaging object is human lungs, and the radio frequency pulse multimode weighting function w(x) adopts:

[0062] w(x)=0.17*(1.05-(1+cos(2*π*(x*10-2000 / 2) / 2000)) / 2*exp(-(π*1e-6*(x*10- 2000 / 2))^2 / (4*log(2)))).

[0063] Methods of obtaining hyperpolarized gas from the subject to be imaged are inhaled through the nasal or oral cavity.

[0064] The gradient echo sequence is a FLASH sequence.

[0065] Others are consistent with Example 1.

[0066] Figure 7 is the result of simulating under-sampled imaging under the K-space center encoding method, Figure 7 A is the template image, Figure 7 Among B is the image that step 4 obtains in the present embodiment (image mean value is 0.0535), Figure 7 C is the image reconstructed by fixed-angle excitation (the average value of the image is 0.0524), Figure 7 Middle D is the image reconstructed by variable-angle excitation (the average value of the imag...

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Abstract

The present invention discloses a radio frequency pulse multimode weighting-based high-resolution fast magnetic resonance imaging method. The method includes the following steps that: a hyperpolarized gas is collected; proton MR positioning imaging is performed, so that position information can be obtained; multimode weighting is performed on different regions of the original K space of an imaging object through using radio frequency pulses, 2-dimensional or 3-dimensional coding is performed on the imaging object in a Cartesian coordinate system, the echo signals of the imaging object are collected; and a reconstructed image is obtained through the echo signals. With the method of the invention adopted, image artifacts in a phase encoding direction caused by a K-space filtering effect can be decreased; the improvement of the SNR of the image can be facilitated; the number of the times of excitation in the phase encoding direction can be reduced, and imaging time can be greatly shortened; and a K-space radio frequency pulse multimode weighting method is adopted, so that more image details can be reserved.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to a high-definition fast magnetic resonance imaging method based on radio frequency pulse multi-mode weighting. It is suitable for dynamic imaging, functional imaging, molecular imaging, and lesion detection with high signal-to-noise ratio, rich details, and short sampling time using hyperpolarized gas as a contrast agent. Background technique [0002] Magnetic Resonance Imaging (MRI), according to the phenomenon that the observed nucleus in the sample is excited by radio frequency pulses in the magnetic field and undergoes nuclear magnetic resonance, the gradient coil is used to encode the sample space, and the electronic system receives the magnetic resonance generated by the sample. The resonance signal is transformed into a spectrum to reconstruct the magnetic resonance image. Conventional MRI is mostly used for H atoms in water or lipids. For inert gas ato...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01R33/56
CPCG01R33/5602
Inventor 周欣谢军帅张会婷孙献平叶朝辉
Owner WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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