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Compound medicine containing licorice roots and colistin for livestock and poultry

A technology of colistin and licorice, applied to medical preparations containing active ingredients, antibacterial drugs, and pharmaceutical formulas, can solve problems such as severe infection, high cost of medication, and economic losses in livestock and poultry breeding, and achieve fast curative effect, The effect of obvious synergy and low cost

Inactive Publication Date: 2016-12-07
GUANGXI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Livestock and poultry infected by Escherichia coli can cause acute sepsis, peritonitis, hepatitis, pneumonia, enteritis and many other serious infections, causing huge economic losses to livestock and poultry breeding
Amoxicillin, norfloxacin, colistin, etc. are commonly used western medicines to prevent and treat such diseases. The situation of drug resistance and drug resistance has not improved, but has been declining
[0004] After searching, there is no relevant report on the combination of licorice and colistin for the treatment of diseases caused by Escherichia coli infection in livestock and poultry

Method used

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  • Compound medicine containing licorice roots and colistin for livestock and poultry

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Embodiment Construction

[0009] The technical solutions and beneficial effects of the present invention will be further described below in conjunction with specific examples. Unless otherwise specified, the weight of licorice in the present invention is the dry weight of licorice.

[0010] 1. Determination of the elimination effect of licorice on colistin resistance

[0011] 1. Measurement method

[0012] Be 1:1, 1:3, 1:5, 1:10, 1:30, 1:50 to prepare the mixed liquid of Radix Glycyrrhizae and various western medicines respectively according to weight ratio; Subculture was carried out by plate dilution method, and the MIC changes of each treatment solution against drug-resistant strains were determined; at the same time, the western medicine without licorice was used as the positive control, and the western medicine without licorice was set as the negative control.

[0013] The above treatments were continuously cultured for 4 generations.

[0014] 2. Test results

[0015] After 4 generations of con...

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Abstract

The invention relates to a compound medicine containing licorice roots and colistin for livestock and poultry. The compound medicine is composed of licorice roots and colistin, and the weight ratio of licorice roots to colistin ranges from 1:3 to 1:10. The invention is further required to protect a compound preparation prepared through the compound medicine for the livestock and poultry. The compound medicine has the advantages of being obvious in synergistic effect, quick in curative effect, low in cost and the like by using colistin and licorice roots according to the specific weight ratio in a combined mode through an experimental study.

Description

technical field [0001] The invention belongs to the technical field of compound medicine for livestock and poultry, in particular to a compound medicine for livestock and poultry containing licorice and colistin, which is used for treating diseases caused by Escherichia coli infection in livestock and poultry. Background technique [0002] Licorice is a perennial herb of the leguminous licorice genus. The roots and rhizomes of licorice have many functions such as invigorating the spleen and Qi, clearing away heat and detoxification, eliminating phlegm and relieving cough, relieving spasms and relieving pain, reconciling medicinal properties, and improving animal immunity. At present, the roots and rhizomes of licorice are often used as feed additives for Chinese herbal medicines. They are rich in drug sources, have no toxic and side effects in animals, have almost no residues, and do not produce drug resistance. Integrate with improving the meat quality of livestock and poul...

Claims

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Application Information

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IPC IPC(8): A61K38/12A61P31/04A61K36/484
CPCA61K38/12A61K36/484A61K2300/00
Inventor 不公告发明人
Owner GUANGXI UNIV
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