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Pulining potassium development based neural cognitive impairment treatment drug and preparation method thereof

A technology for cognitive impairment and drug treatment, applied in the field of neurocognitive disorder treatment drugs, can solve problems such as few drugs for neurocognitive disorder treatment, improve the internal and external environment of the body, have obvious synergistic effects, treat or relieve Neurasthenic effects

Inactive Publication Date: 2016-12-07
杨添福
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Pulinin Potassium has a good therapeutic effect on the treatment of neurocognitive disorders, but currently there are few drugs that use Pulinin Potassium to treat neurocognitive disorders

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The present invention provides a technical solution: a drug for the treatment of neurocognitive disorders developed based on Pulinin Potassium, comprising the following components by weight: 20 parts of Pulinin Potassium, 10 parts of ferulic acid, 4 parts of baicalin, nitrobenzene 4 parts of Dipin, 15 parts of excipients, 5 parts of Panax notoginseng, 7 parts of Gardenia.

[0023] The auxiliary materials include the following components by weight: 2 parts of salvia miltiorrhiza, 1 part of licorice, 3 parts of oryzanol, 4 parts of cobalamin, 2 parts of American ginseng, 2 parts of Fushen, and 1 part of scopolamine.

[0024] A preparation method based on a drug for the treatment of neurocognitive disorders developed by Pulinin Potassium, comprising the following steps:

[0025] S1: Weighing and proportioning, weigh the required Pulinin potassium, ferulic acid, baicalin, nifedipine, excipients, Panax notoginseng, and gardenia according to the established component ratio, a...

Embodiment 2

[0033] The invention provides a technical solution: a drug for treating neurocognitive disorders developed based on Pulinin Potassium, comprising the following components by weight: 25 parts of Pulinin Potassium, 13 parts of ferulic acid, 5 parts of baicalin, nitrobenzene 6 parts of Dipin, 20 parts of excipients, 7 parts of Panax notoginseng, 9 parts of Gardenia.

[0034] The auxiliary materials include the following components by weight: 3 parts of salvia miltiorrhiza, 1.5 parts of licorice, 4 parts of oryzanol, 5 parts of cobalamin, 3 parts of American ginseng, 2.5 parts of Fushen, and 1 part of scopolamine.

[0035] A preparation method based on a drug for the treatment of neurocognitive disorders developed by Pulinin Potassium, comprising the following steps:

[0036] S1: Weighing and proportioning, weigh the required Pulinin potassium, ferulic acid, baicalin, nifedipine, excipients, Panax notoginseng, and gardenia according to the established component ratio, and place th...

Embodiment 3

[0044] The invention provides a technical solution: a drug for the treatment of neurocognitive disorders developed based on Pulinin Potassium, comprising the following components by weight: 32 parts of Pulinin Potassium, 16 parts of ferulic acid, 7 parts of baicalin, nitrobenzene 8 parts of Dipin, 25 parts of excipients, 10 parts of Panax notoginseng, 14 parts of Gardenia.

[0045] The auxiliary materials include the following components by weight: 3 parts of salvia miltiorrhiza, 3 parts of licorice, 5 parts of oryzanol, 6 parts of cobalamin, 3.5 parts of American ginseng, 3 parts of Fushen, and 1.5 parts of scopolamine.

[0046] A preparation method based on a drug for the treatment of neurocognitive disorders developed by Pulinin Potassium, comprising the following steps:

[0047] S1: Weighing and proportioning, weigh the required Pulinin potassium, ferulic acid, baicalin, nifedipine, excipients, Panax notoginseng, and gardenia according to the established component ratio, a...

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Abstract

The invention discloses a Pulining potassium development based neural cognitive impairment treatment drug. The Pulining potassium development based neural cognitive impairment treatment drug comprises, by weight, 20-40 parts of Pulining potassium, 10-20 parts of ferulic acid, 4-8 parts of baicalin, 4-9 parts of nifedipine, 15-30 parts of auxiliary materials, 5-12 parts of pseudo-ginseng and 7-16 parts of fructus Gardeniae. The invention further discloses a preparation method of the Pulining potassium development based neural cognitive impairment treatment drug. The preparation method includes the steps of S1, weighing and matching; S2, preparation of the auxiliary materials; S3, preparation of auxiliary liquid; S4, filtration of the auxiliary materials; S5, preparation of raw materials; S6, crystallization of the drug; S7, final formation. The Pulining potassium development based neural cognitive impairment treatment drug can be used for treating cognitive impairment especially for treating and relieving to improve senile dementia, vascular dementia, mild cognitive impairment and amnesia as well as relieving pain and calming analgesia, inside and outside environment of a human body can be improved, and various symptoms of neurasthenia can be treated or alleviated.

Description

technical field [0001] The invention relates to the technical field of medicines for treating neurocognitive disorders developed based on Potassium Pulinin, in particular to a medicine for treating neurocognitive disorders developed based on Potassium Pulinin and a preparation method thereof. Background technique [0002] Cognitive impairment is a common core symptom of mild cognitive impairment (MCI), dementia and amnesia, which seriously affects the lives of patients. MCI is an excessive and pre-dementia pathological state between normal aging cognitive decline and very mild Alzheimer's disease (AD) and vascular dementia (vascular dementia, VD). The earliest stage, first reported in 1990, is characterized by acquired cognitive dysfunction without significant decline in activities of daily living. The prevalence of MCI fluctuates between 3% and 20%, and it is also considered to be between 20% and 30%. On average, 10% to 15% of MCI develops into dementia every year. The dia...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61K36/81A61P25/28A61P25/00A61K31/522A61K31/192A61K31/4422A61K31/575A61K31/7048A61K31/714
CPCA61K31/522A61K31/192A61K31/4422A61K31/575A61K31/7048A61K31/714A61K36/076A61K36/258A61K36/484A61K36/537A61K36/744A61K36/81A61K2300/00
Inventor 杨添福
Owner 杨添福
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