Bamboo leaf flavone composite nanoparticles with whitening effect and preparation method thereof
A technology of composite nanoparticles and bamboo leaf flavonoids, which is applied in the field of daily chemicals, can solve the problems of limiting the application of whitening preparations, low solubility of bamboo leaf flavonoids, and difficult skin absorption, etc., and achieves excellent tyrosinase activity inhibition, particle size Uniform and controllable, strong whitening effect
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Embodiment 1
[0050] Embodiment 1, a kind of bamboo leaf flavone composite nanoparticle preparation method with whitening effect:
[0051] (1) Dissolve 4 mg of bamboo leaf flavonoids in 2 mL of distilled water, heat and stir to dissolve;
[0052] (2) Add 24 mg of bamboo leaf polysaccharide to the solution obtained in step (1) and stir to dissolve to obtain bamboo leaf flavonoids- bamboo leaf polysaccharide solution;
[0053] (3) Dissolve 2 mg of ε-polylysine in 1 mL of distilled water;
[0054] (4) Drop the solution obtained in step (3) into the bamboo leaf flavone-bamboo polysaccharide solution for 1 minute (ie, at a flow rate of about 200mL / h) under the condition of magnetic stirring at a rotational speed of 100-300r / min;
[0055] (5) Continue to stir at a low speed (100-300r / min) for 30 minutes, and the obtained opalescent suspension is bamboo leaf flavonoid composite nanoparticle solution (I) with whitening effect.
Embodiment 2
[0056] Embodiment 2, a kind of bamboo leaf flavonoid composite nanoparticle preparation method with whitening effect:
[0057] (1) Dissolve 4 mg of bamboo leaf flavonoids in 2 mL of distilled water, heat and stir to dissolve;
[0058] (2) Add 36 mg of bamboo leaf polysaccharide to the solution obtained in step (1) and stir to dissolve to obtain bamboo leaf flavonoids- bamboo leaf polysaccharide solution;
[0059] (3) 2 mg of ε-polylysine was dissolved in 2 mL of distilled water;
[0060] (4) Drop the solution obtained in step (3) into the bamboo leaf flavone-bamboo polysaccharide solution for 1 minute (ie, at a flow rate of about 300mL / h) under the condition of magnetic stirring at a rotational speed of 100-300r / min;
[0061] (5) Continue to stir at a low speed for 30 minutes, and the obtained opalescent suspension is bamboo leaf flavonoid composite nanoparticle solution (II) with whitening effect.
Embodiment 3
[0062] Embodiment 3, a kind of preparation method of composite nanoparticle of bamboo leaf flavonoids with whitening effect:
[0063] (1) Dissolve 4mg of bamboo leaf flavonoids in 16mL of distilled water, heat and stir to dissolve;
[0064] (2) Add 50 mg of coriander root polysaccharide into the solution obtained in step (1) and stir to dissolve to obtain bamboo leaf flavonoid-coriander root polysaccharide solution;
[0065] (3) 10 mg of ε-polylysine was dissolved in 4 mL of distilled water;
[0066] (4) Drop the solution obtained in step (3) into the bamboo leaf flavonoid-corydalone polysaccharide solution for 6 minutes (that is, at a flow rate of about 200mL / h) under the condition of magnetic stirring at a rotational speed of 100-300r / min;
[0067] (5) Continue stirring at a low speed for 30 minutes, and the obtained opalescent suspension is bamboo leaf flavonoid composite nanoparticle solution (III) with whitening effect.
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