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Method for calculating 19 biological parameters related to light absorption of human skin with mathematical model

A mathematical model and light absorption technology, applied in the field of computational biology, can solve problems such as high cost of testing, time-consuming and laborious, and difficult to guarantee the accuracy of test results, and achieve accurate and reliable models

Active Publication Date: 2016-08-17
陈威
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

If you want to obtain the values ​​of all the above parameters, you need to conduct several inspection experiments, which not only requires high inspection costs, but also takes time and effort, and there are experimental errors in manual inspections, and the accuracy of inspection results is difficult to guarantee.

Method used

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  • Method for calculating 19 biological parameters related to light absorption of human skin with mathematical model
  • Method for calculating 19 biological parameters related to light absorption of human skin with mathematical model
  • Method for calculating 19 biological parameters related to light absorption of human skin with mathematical model

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Effect test

Embodiment 1

[0048] The steps of the skin spectrum model include steps 1 to 3:

[0049] Step 1: According to the characteristics of absorption, reflection, scattering, and transmission when visible light irradiates the skin, the skin is abstracted from top to bottom into four layers: rough skin layer, epidermis layer, dermis layer, and subcutaneous tissue layer.

[0050] Surface layer: no actual thickness, infinitely thin, located in the outermost layer, connected with the external environment on the top and the epidermis on the bottom;

[0051] Epidermis: the actual first layer of the skin, with a limited thickness, connected to the rough surface layer, and connected to the dermis layer below;

[0052] Dermis: the actual second layer of the skin, with a limited thickness, connected to the epidermis on the top and connected to the subcutaneous tissue on the bottom;

[0053] Hypodermis Layer: The hypodermis has infinite thickness, does not describe any composition, and functions to absorb ...

Embodiment 2

[0065] From the assumption of the skin, it can be known that the various absorption components in the skin are independent of each other, so the absorption coefficient can be expressed as a linear combination of the absorption of each component.

[0066] Step 4 establishes the relationship between the absorption coefficient and the volume fraction of melanin in the epidermis, the concentration of eutectic melanin in the epidermis, the concentration of pheomelanin in the epidermis, the volume fraction of water in the epidermis, the volume fraction of oil in the epidermis, and the volume fraction of oil in the epidermis. Equation for the relationship between carotene concentrations.

[0067] The mathematical relationship between the epidermal absorption coefficient and the corresponding component parameters can be as follows:

[0068] σ a e ...

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Abstract

The invention relates to a method for calculating 19 biological parameters related to the light absorption of the human skin with a mathematical model. The method comprises the steps that two levels of analyzing models, namely, the skin spectral analyzing model and the skin and light absorption related biological parameter mathematical model, are established, so that correlation is established between the skin spectrum and skin epidermis, and between the corium layer and biological parameters related to light absorption, and it is achieved that virtual spectra are simulated through one set of skin parameters, optimizing iteration is carried out through the virtual spectra and practical spectra with the information processing technology, a set of optimal solutions can be found, the assigned fitting degree standard can be met, and the purpose of quantitative analysis of the biological parameters related to the light absorption of the human skin can be achieved.

Description

technical field [0001] The present invention relates to computational biology, relates to a method for establishing an analysis model of skin spectrum and a modeling method for biological parameters related to human skin light absorption, in particular to a mathematical model for 19 biological parameters related to human skin light absorption Methods. Background technique [0002] The interaction between light and matter will cause electronic transitions in the energy levels of atoms and molecules inside the matter, causing changes in wavelength and intensity information in the absorption, reflection, and scattering of light by the matter. Spectrometers can be used to detect and process such changes. Compared with other analytical methods, spectral detection has the characteristics of non-destructive, high sensitivity, and high precision, so it has been widely used in the detection and identification of various materials. [0003] Biological and optical studies have shown t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F17/11G06F17/50
CPCG06F17/11G06F30/20A61B5/72A61B5/0059A61B5/443G01N21/31G01N2201/129A61B5/0075G01N21/47
Inventor 陈威
Owner 陈威
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