Animal model preparation system for obstructive sleep breathing disorder

Abstract

The invention relates to the technical field of medical experiment, in particular to an obstructive sleep respiratory disorder disease animal model preparation system. The obstructive sleep respiratory disorder disease animal model preparation system comprises a head cap and a simulation container device, wherein the first end of the simulation container device is communicated with the inside of the head cap; the corresponding second end of the simulation container device is used for connecting an air source; a first valve is arranged between the simulation container device and the air source; one end of the head cap is open; the head cap is used for externally sleeving on a target animal; the opening of the head cap can be connected with the neck part of the target animal in a sealed way; a pressure stabilization device is connected onto the simulation container device; the pressure stabilization device presets a pressure threshold value and is used for controlling the on-off state of an air path inside and outside the simulation container device. The invention aims at providing the obstructive sleep respiratory disorder disease animal model preparation system for improving the knowing and treatment on an obstructive sleep respiratory disorder disease.

Description

technical field [0001] The invention relates to the technical field of medical experiments, in particular to a system for preparing animal models of obstructive sleep-disordered breathing. Background technique [0002] With the development of social and economic conditions, the medical industry has gradually attracted widespread attention, and people have paid more and more attention to the research of sleep-related diseases. A large number of epidemiological statistics show that obstructive sleep-disordered breathing is a disease that affects human sleep quality and even physical health. Since the 1980s, scholars at home and abroad have been exploring and establishing animal models of this disease so that people can understand, study, and treat obstructive sleep-disordered breathing. [0003] In the prior art, animal models of intermittent hypoxia have been gradually applied since the 1990s; this type of model preparation system is to keep experimental animals in airtight c...

AI Technical Summary

Problems solved by technology

However, this model cannot completely simulate obstructive sleep-disordered breathing disease, that is, the model cannot simulate two important pathological factors: one is airway obstruction, and the other is negative inspiratory pressure.

Without these two factors, it is impossible to simulate the pathophysiological process of humans suffering from obstructive sleep-disordered breathing disease, so that it cannot provide a true and reliable basis for future treatment

[0004] No suitable animal modeling method has been found so far, which seriously restricts the understanding and treatment of obstructive sleep disordered breathing disease

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