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Compound stabilizer and kit for in vitro diagnosis reagents

A compound stabilizer and in vitro diagnostic technology, applied in the biological field, can solve the problems of low stability of in vitro diagnostic reagents, achieve good stabilization effect, improve stability, and be convenient to use

Active Publication Date: 2016-05-25
SHENYANG BAICHUANGTE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The object of the present invention is to provide a composite stabilizer for in vitro diagnostic reagents, which is used to solve the defects of low stability of in vitro diagnostic reagents in the prior art

Method used

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  • Compound stabilizer and kit for in vitro diagnosis reagents
  • Compound stabilizer and kit for in vitro diagnosis reagents
  • Compound stabilizer and kit for in vitro diagnosis reagents

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The composite stabilizer used for in vitro diagnostic reagents prepared by the present embodiment consists of:

[0045]

[0046] The preparation method of described composite stabilizer is:

[0047] 1) Weigh 5 g of bovine serum albumin, 2 g of casein, 0.8 g of dithiothreitol, 3 g of sodium borate and 10 g of trehalose according to the content of the components, and fully dissolve the above components in 30 mL of ultrapure water, Mix to obtain solution 1;

[0048] 2) Measure 20mL of propylene glycol, 202mL of Tween and 9501mL of ProClin according to the content of the components, and add them to solution 1, mix well to obtain solution 2;

[0049] 3) Dilute solution 2 to 100mL with ultrapure water to obtain the composite stabilizer.

Embodiment 2

[0051] The composite stabilizer used for in vitro diagnostic reagents prepared by the present embodiment consists of:

[0052]

[0053]

[0054] The preparation method is the same as in Example 1.

Embodiment 3

[0056] The composite stabilizer used for in vitro diagnostic reagents prepared by the present embodiment consists of:

[0057]

[0058] The preparation method is the same as in Example 1.

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Abstract

The invention belongs to the technical field of biology, and particularly relates to a compound stabilizer and a kit for in vitro diagnosis reagents. The compound stabilizer comprises a sealing agent, a surfactant, a micromolecule organic reductant, a nucleic acid ingredient stabilizer, a biological active substance protecting agent and a biological preservative. The compound stabilizer can be universally applied to various in vitro diagnosis reagents and has better reagent stabilizing effect, and validity period of the reagents is prolonged effectively.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a composite stabilizer for in vitro diagnostic reagents and a kit. Background technique [0002] In vitro diagnostic reagents can be used alone or in combination with instruments, appliances, equipment or systems to examine human samples in vitro and to detect or measure a certain component in the sample. Chemical, biological Or immunology and other substances. The in vitro diagnostic reagent system includes many components such as detection reagents, reagent supplies, calibration objects (products), quality control objects (products), etc. In vitro diagnostic reagents have been widely used in medical research and clinical testing, and are an indispensable part of routine medical procedures. In vitro diagnostic reagents with stable and reliable quality can provide accurate clinical test data and play an important role in the prevention and control of diseases as well as...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/58C12Q1/50C12Q1/52
CPCC12Q1/50C12Q1/52C12Q1/58
Inventor 李伟东
Owner SHENYANG BAICHUANGTE BIOTECH
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