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Non-alcoholic fatty liver disease prevention and control compound preparation and use thereof

A fatty liver disease, non-alcoholic technology, applied in the field of traditional Chinese medicine compound preparations for the prevention and treatment of NAFLD, can solve the problems of certain drugs, easy to relapse, and difficult for patients to persist for a long time

Active Publication Date: 2016-05-11
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] There is no ideal therapeutic drug for NAFLD. At present, a large number of drugs for the treatment of NAFLD can regulate lipid metabolism, anti-oxidation, improve IR, etc., and more or less show certain therapeutic effects, but there is no completely effective and definite drug available. Clinical use, and long-term use of these drugs has certain toxicity, so it is difficult for patients to persist for a long time, and it is easy to relapse after stopping the drug

Method used

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  • Non-alcoholic fatty liver disease prevention and control compound preparation and use thereof
  • Non-alcoholic fatty liver disease prevention and control compound preparation and use thereof
  • Non-alcoholic fatty liver disease prevention and control compound preparation and use thereof

Examples

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Effect test

Embodiment 1

[0024] The raw materials were weighed according to the following weights: Gynostemma 30g, Astragalus 20g, Angelica 10g, Polygonum cuspidatum 30g, Fritillaria 6g, prepared into decoction, granules, tablets, capsules or oral liquid according to conventional techniques.

Embodiment 2

[0026] The raw materials were weighed according to the following weights: Gynostemma pentaphyllum 40g, Radix Astragali 30g, Angelica sinensis 15g, Polygonum cuspidatum 20g, Fritillaria 9g, prepared into decoction, granules, tablets, capsules or oral liquid according to conventional techniques.

Embodiment 3

[0028] The raw materials were weighed according to the following weights: Gynostemma pentaphyllum 50g, Radix Astragali 15g, Angelica sinensis 30g, Polygonum cuspidatum 15g, Fritillaria 10g, prepared into decoction, granules, tablets, capsules or oral liquid according to conventional techniques.

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Abstract

The present invention discloses a non-alcoholic fatty liver disease prevention and control compound preparation, and the innovation is that: the compound preparation is composed of the following parts by weight of medicinal raw materials: 15 to 60 parts of gynostemma, 15 to 45 parts of astragalus root, 10 to 30 parts of Chinese angelica, 15 to 45 parts of polygonum cuspidatum and 6 to 12 parts of bulbus fritillariae thunbergii. The compound preparation can be prepared into tablets, granules, capsules or oral solutions by conventional methods. Pharmacodynamics shows that the compound preparation has a significant effect of improvement and prevention of fatty degeneration of liver of non-alcoholic fatty liver disease and reduction of serum transaminases.

Description

technical field [0001] The invention belongs to the field of research, development and utilization of traditional Chinese medicine, and in particular relates to a compound traditional Chinese medicine preparation for preventing and treating NAFLD and its application. Background technique [0002] Nonalcoholic fatty liver disease (NAFLD) summarizes a class of diseases from simple fatty liver, nonalcoholic steatohepatitis (NASH) to liver fibrosis and even liver cirrhosis. With the prevalence of obesity and diabetes, the incidence of NAFLD has risen rapidly, becoming one of the most important pathogenic factors of chronic liver disease. In Western populations, the incidence of NAFLD is 25-30%, and it is as high as 80% in obese and diabetic patients, becoming the primary cause of abnormal liver enzymes. In my country, due to changes in dietary structure and lifestyle, the incidence of NAFLD has gradually increased, and it has become the second largest liver disease after viral ...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P1/16
Inventor 宋海燕季光邢练军刘洋杨丽丽舒祥兵
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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