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Iron-replenishment liquid pharmaceutical preparation and preparation method thereof

A technology of liquid preparation and iron supplementation, which is applied in the direction of medical preparations containing active ingredients, blood diseases, pharmaceutical formulas, etc. It can solve problems such as difficult realization and complicated process, and achieve enhanced intelligence, good sense and taste, and good safety Effect

Active Publication Date: 2016-04-13
聪睿慧康(北京)科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But in the prior art, the technology that ferrous glycinate is used as iron supplement preparation is less, and the technology that it is made into liquid preparation is mostly complicated, is difficult for realizing, and the liquid preparation that makes has bad smells such as iron fishy, ​​thus it can be seen that it can Whether to prepare a liquid iron supplement preparation containing ferrous glycinate, so that it has the advantages of good taste, high stability, high absorption rate, and simple preparation process has become a technical problem to be solved urgently by those skilled in the art

Method used

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  • Iron-replenishment liquid pharmaceutical preparation and preparation method thereof
  • Iron-replenishment liquid pharmaceutical preparation and preparation method thereof
  • Iron-replenishment liquid pharmaceutical preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A liquid preparation for iron supplementation, comprising the following components in parts by weight:

[0023]

[0024] The liquid preparation is any one of oral drops, oral liquid or beverage.

[0025] A method for preparing a liquid preparation for iron supplementation, comprising the following steps: taking 30% by mass of erythritol, 0.1% of polydextrose and 0.1% of aspartame, adding water and fully stirring Dissolve to obtain solution A, get respectively the potassium sorbate of 0.1% and the citric acid of 1.0% by mass percent and add water to dissolve respectively and obtain solution B, solution C, add mass percent in solution A and be 0.2% ferrous glycinate, be warming up to 80 Keep at ℃ for 30 minutes, then add solution B and solution C to it, mix well to obtain a mixed solution, add 0.01% essence by mass percentage, 10% sodium carboxymethyl cellulose to the mixed solution, and add water to make up to 100 %, heated to 100°C and kept for 10 minutes, measured ...

Embodiment 2

[0027] A liquid preparation for iron supplementation, comprising the following components in parts by weight:

[0028]

[0029] The liquid preparation is any one of oral drops, oral liquid or beverage.

[0030] A method for preparing a liquid preparation for iron supplementation, comprising the following steps: taking 20% ​​by mass of erythritol, 0.2% of polydextrose and 0.08% of aspartame, adding water and fully stirring Dissolving to obtain solution A, respectively getting 0.2% potassium sorbate and 0.8% citric acid to dissolve in water respectively to obtain solution B and solution C, adding 0.3% ferrous glycinate and 0.02% ferrous glycinate to solution A ferrous sulfate and 0.08% hemin, the temperature was raised to 90°C and kept for 30min, then solution B and solution C were added thereto, mixed thoroughly to obtain a mixed solution, and 0.02% by mass percentage was added to the mixed solution essence, 8% sodium carboxymethyl cellulose, add water to make up to 100%, h...

Embodiment 3

[0032] A liquid preparation for iron supplementation, comprising the following components in parts by weight:

[0033]

[0034]

[0035] The liquid preparation is any one of oral drops, oral liquid or beverage.

[0036]A method for preparing a liquid preparation for iron supplementation, comprising the following steps: taking 18% by mass of erythritol, 0.3% of polydextrose and 0.07% of aspartame, adding water and fully stirring Dissolve to obtain solution A, get respectively the potassium sorbate of 0.3% and the citric acid of 0.5% to add water to dissolve respectively and obtain solution B, solution C after mass percent, add the ferrous glycinate that mass percent is 0.4% in solution A, be warming up to Keep at 95°C for 30 minutes, then add solution B and solution C to it, mix thoroughly to obtain a mixed solution, add 0.05% essence by mass percentage, 7% sodium carboxymethyl cellulose to the mixed solution, and add water to make up to 100%, heat to 100°C and keep for ...

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PUM

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Abstract

The invention relates to healthcare products, in particular to an iron-replenishment liquid pharmaceutical preparation and a preparation method thereof. The iron-replenishment liquid pharmaceutical preparation comprises, by weight, 0.2-0.6% of ferrous bisglycinate, 10-30% of erythritol, 0.1-0.5% of polydextrose, 0.01-0.1% of aspartame, 0.1-0.5% of potassium sorbate, 0.1-1.0% of citric acid, 0.01-0.1% of essence, 1-10% of sodium carboxymethylcellulose and water supplemented to 100%. The method is simple in preparation technique and low in cost, and the prepared iron-replenishment liquid pharmaceutical preparation is uniform in color, high in stability and free of objectionable odor such as rust.

Description

technical field [0001] The invention relates to health products, in particular to a liquid preparation for iron supplementation and a preparation method thereof. Background technique [0002] Iron is one of the essential elements that make up the human body. Iron deficiency will affect the health and development of the human body. The biggest impact is iron deficiency anemia. The survey by the World Health Organization shows that about 50% of girls, 20 Iron deficiency anemia occurs in 40% of adult women and 40% of pregnant women. Iron supplementation is the process of supplementing the human body with necessary and appropriate amounts of inorganic iron or organic iron compounds through food or special nutrients, so as to supplement iron elements to achieve the purpose of strengthening the body, preventing or assisting the treatment of diseases. Iron supplementation is the process of supplementing the human body with necessary and appropriate amounts of inorganic iron or org...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/198A61P3/12A61P7/06
Inventor 张伟张睿哲
Owner 聪睿慧康(北京)科技发展有限公司
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