Non-invasive spine marrow lesion detector

Abstract

The invention discloses a non-invasive spine marrow lesion detector. According to the invention, optical signals carrying marrow information are converted into electric signals by detecting units through near infrared technology; data is obtained through signal processing; hemodynamic parameters of the marrow can be obtained according to the modified Beer-Lambert law; and therefore spine marrow lesions can be diagnosed. The detector is noninvasive, can continuously and rapidly diagnose lesions, is low in cost and quite high in reliability, is suitable for diagnosing spine marrow lesions, and can effectively avoid a phenomena that patients are in pain when the patients are diagnosed through other methods.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a non-invasive spinal bone marrow lesion detector. Background technique [0002] Bone marrow is a connective tissue rich in cells in the bone, which has important functions such as hematopoiesis, production of coagulation factors, and immunity. Bone marrow lesions include bone marrow infiltration lesions caused by tumor tissue invasion of bone marrow and bone marrow inflammatory exudation edema caused by inflammation, trauma and other diseases. Among them, multiple myeloma (MM) is a malignant plasma cell disease, and its tumor cells originate from the abnormal proliferation of plasma cells in the bone marrow, and plasma cells are cells that develop to the final functional stage of B lymphocytes. Therefore, multiple myeloma can be classified as B lymphocyte lymphoma. Currently, WHO classifies it as a type of B-cell lymphoma called plasma cell myeloma / plasma cell tumor. It is char...

AI Technical Summary

Problems solved by technology

[0003] After reviewing the existing methods of clinical diagnosis of spinal bone marrow lesions are: (1) bone marrow biopsy, bone marrow fluid samples are extracted through bone marrow puncture, and the spinal bone marrow lesions are detected by analyzing the degree of proliferation in the bone marrow tissue, the degree of plasma cell infiltration and the mode of proliferation, etc. Diagnosis, but this invasive diagnostic method is very painful for patients, and it is difficult to confirm the diagnosis continuously. At the same time, the bone puncture site is relatively blind and has the possibility of failure and misdiagnosis. difficult for patients to accept

(2) X, CT, and MRI observe spinal cord images to diagnose spinal bone marrow lesions. Although this method is non-invasive, it is very expensive and the cost is too high

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