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Systems and methods for classifying and characterizing tissue using first and second order statistics for quantitative ultrasound parameter mapping

A technology of ultrasound system and parameters, which is used in ultrasound/sonic/infrasonic Permian technology, ultrasound/sonic/infrasound image/data processing, health index calculation, etc.

Active Publication Date: 2019-10-18
SUNNYBROOK RES INST
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, conventional B-mode images can also represent undesired changes in texture estimates due to changes in instrument settings, ultrasound beam diffraction, and attenuation effects

Method used

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  • Systems and methods for classifying and characterizing tissue using first and second order statistics for quantitative ultrasound parameter mapping
  • Systems and methods for classifying and characterizing tissue using first and second order statistics for quantitative ultrasound parameter mapping
  • Systems and methods for classifying and characterizing tissue using first and second order statistics for quantitative ultrasound parameter mapping

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Embodiment Construction

[0022] Described herein are some systems and methods for characterizing tissue using quantitative ultrasound techniques. The parameters are calculated directly from the raw echo signal data acquired from the region of interest during an ultrasound scan. Preferably, these parameters are calculated after normalizing the echo signal data using reference data to reduce the influence of variations in instrument settings, ultrasound beam diffraction and attenuation effects. For example, quantitative ultrasound ("QUS") parameters such as mid-band fit ("MBF"), spectral slope ("SS"), spectral 0-Mhz intercept ("SI"), spacing between scatterers can be calculated ("SAS"), Effective Scatterer Diameter ("ESD"), and Effective Acoustic Concentration ("EAC"), from which a parametric map associated with the region of interest is generated First and second order statistics are computed from these parametric maps The metric is used to characterize the tissue or tissues in the region of interest....

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Abstract

Systems and methods for classifying tissue using quantitative ultrasound techniques. Parameters are calculated directly from raw echo signal data acquired from a region of interest during an ultrasound scan and used to generate a parameter map. These parameters were calculated after normalizing the echo signal data with reference data to reduce the influence of variations in instrument settings, ultrasound beam diffraction and attenuation effects. First and second order statistical measures are computed from these parametric maps and used to classify the tissue or tissues in the region of interest. Using these systems and methods, organizations can be classified using different classification levels. For example, tissue characterized as malignant cancer can be additionally graded (eg, grade I, II or III).

Description

Background technique [0001] The field of the invention is systems and methods for quantitative ultrasound ("QUS"). More specifically, the present invention relates to systems and methods for classifying and representing tissue as associated with a particular histological state using QUS. [0002] Clinical ultrasound is a useful and non-invasive tool for diagnosing cancer and other diseases. In addition to ultrasound's ability to noninvasively distinguish malignant from benign tumors, the ability to represent malignancies according to their histological grade is of paramount importance for staging and treatment design. The comparative interpretation of conventional B-mode images becomes difficult when different ultrasound machines are used, or when different settings are applied due to the many instrument parameters that can be selected during an ultrasound imaging session. Furthermore, B-mode images lack information about the microstructural properties of soft tissues. [0...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B8/08A61B5/103G01N29/44G01N33/483G06V10/764
CPCA61B8/08A61B8/0825A61B8/469A61B8/5207A61B8/5223G06T7/0012A61B8/587G01N33/4833G06T2207/10132G06T2207/30096A61B8/14G16H50/30G06V10/758G06V2201/032G06V10/764G06F18/2411A61B8/085G06T2207/30024G06T2207/30204G06T7/11
Inventor A·萨德吉-奈尼H·塔达扬G·J·恰尔诺塔O·法露
Owner SUNNYBROOK RES INST
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