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Surface plasmon resonance (SPR) biochemical analyzer

A technology of surface plasmon and biochemical analyzers, which is applied in the direction of analyzing materials, analyzing materials through optical means, instruments, etc., can solve the problems of low sales and high prices, and achieve wide application range, good commercial performance, The effect of high precision and sensitivity

Inactive Publication Date: 2016-02-17
富强
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Due to the high price, not many are sold, only a few

Method used

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  • Surface plasmon resonance (SPR) biochemical analyzer

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Embodiment Construction

[0017] Such as figure 1 As shown, a schematic diagram of the system structure of a surface plasmon resonance (SPR) biochemical analyzer of the present invention. The figure includes: carrier liquid 1, peristaltic pump 2, sample 3, injection valve 4, flow cell 5, sensor chip 6, prism 7, LD module 8, optical receiver module 9; its structural features are: carrier liquid 1 Pass through the peristaltic pump 2, after passing through the peristaltic pump 2, enter the injection valve 4, through the injection valve 4 to change the flow rate and flow of the carrier liquid 1, and then the carrier liquid 1 enters the flow cell 5 to clean the pipeline and flow cell 5 ; In addition, when the sample enters the injection valve 4, the peristaltic pump 2 and the injection valve 4 are reversed, and the sample is sucked into the pipeline first, and then the peristaltic pump 2 and the injection valve 4 are rotated forward again, and the sample is pushed into the flow cell. reaction.

[0018] figur...

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Abstract

The invention relates to a surface plasmon resonance (SPR) biochemical analyzer. The surface plasmon resonance (SPR) biochemical analyzer has the advantages of high precision and sensitivity as well as wide application scope, can be used by many users, and has good commercialization performance. The surface plasmon resonance (SPR) biochemical analyzer mainly comprises a mechanical scanning system, an optical system and a fluid injection / analysis system, wherein the fluid injection / analysis system comprises a carrier fluid, a peristaltic pump, a sample, a sampling valve, a flow cell, a sensing chip, a prism, a LD module and a light receiver module; a structure of the surface plasmon resonance (SPR) biochemical analyzer is characterized in that the carrier fluid passes through the peristaltic pump, then is introduced into the sampling valve from the peristaltic pump, flow velocity and flow amount of the carrier fluid can be changed by the sampling valve, then the carrier fluid is introduced into the flow cell, a pipeline and the flow cell are cleaned; in addition, a sample is introduced into the sampling valve, the peristaltic pump and the sampling valve are reversed, the sample is sucked into the pipeline, then the peristaltic pump and the sampling valve are co-rotated, and the sample is pushed into the flow cell for being reacted.

Description

Technical field [0001] The invention belongs to a new type of biochemical analysis system widely used in the field of biochemical analysis, and specifically relates to a surface plasmon resonance (SPR) biochemical analyzer. Background technique [0002] The 21st century is the era of life sciences. Understanding and studying life phenomena at the molecular level is a hot spot in current research. In recent years, an advanced biochemical analysis method and technology—Surface Plasmon Resonance (SPR) testing technology has received extensive attention and rapid development. [0003] SPR technology is an analysis technology based on physical optical characteristics. When using optical SPR technology to determine, a reactant (such as a ligand) is fixed on the metal film on the surface of the sensor chip, and the sample (receptor) containing the analyte is The constant velocity passes through the sensor chip and interacts with the molecules on the sensor chip, causing changes in the op...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/552
Inventor 富强田志安
Owner 富强
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