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Polyglycolic acid anti-infection surgical suture and preparation method

A polyglycolic acid, surgical suture technology, applied in the field of medical materials, can solve the problems of surgical wound suture and inconvenient healing, and achieve the effects of promoting wound healing, no toxic side effects, and high tensile strength

Inactive Publication Date: 2016-01-20
钊桂英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Natural materials and artificial materials have their own advantages and disadvantages, which cause inconvenience to the suturing and healing of surgical wounds. Therefore, in order to improve the performance of existing absorbable sutures, a surgical suture with anti-infection and high tensile strength can be developed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 A polyglycolic acid anti-infection surgical suture, which is mainly prepared from the following raw materials (10g per portion): 4 parts of chrysanthemum, 8 parts of Jiubing, 7 parts of Changshan, 6 parts of Guizhi, 12 parts of stamen, and 4 parts of Peilan 9 parts of Daqingye, 10 parts of Paojiang, 8 parts of lotus pod, 5 parts of Wulingzhi, 7 parts of Zizhucao, 3 parts of Puhuang (charcoal), 9 parts of sea octopus, 30 parts of polyglycolic acid, 12 parts of chitin, 3 parts of crosslinking agent, 2 parts of stabilizer, 1 part of antibacterial agent.

[0028] The preparation method of above-mentioned a kind of polyglycolic acid anti-infective surgical suture is:

[0029] (1) Remove impurities and wash the rescue Bing, Changshan and Daqingye, add rice wine and mix well, put it in a pot and steam it thoroughly, take it out, let it cool, chop it up, stir-fry it until the surface is dry, take it out, and dry it in the air;

[0030] (2) Crack the stamen into smal...

Embodiment 2

[0034] Example 2 A polyglycolic acid anti-infection surgical suture, which is mainly prepared from the following raw materials (10g per portion): 10 parts of chrysanthemum, 15 parts of Jiubingying, 14 parts of Changshan, 11 parts of Guizhi, 18 parts of stamens, and 10 parts of Peilan 13 parts of Daqingye, 14 parts of Paojiang, 15 parts of lotus pod, 9 parts of Wulingzhi, 12 parts of Zizhucao, 7 parts of Puhuang (charcoal), 12 parts of sea octopus, 50 parts of polyglycolic acid, 15 parts of chitin, 9 parts of cross-linking agent, 6 parts of stabilizer, 4 parts of antibacterial agent.

[0035] A preparation method of polyglycolic acid anti-infection surgical suture is:

[0036] (1) Remove impurities and wash the rescue Bing, Changshan and Daqingye, add rice wine and mix well, put it in a pot and steam it thoroughly, take it out, let it cool, chop it up, stir-fry it until the surface is dry, take it out, and dry it in the air;

[0037] (2) Crack the stamen into small pieces, p...

Embodiment 3

[0042] Example 3 A polyglycolic acid anti-infection surgical suture, which is mainly prepared from the following raw materials (10g each): 5 parts of chrysanthemum, 10 parts of Jiubingying, 9 parts of Changshan, 8 parts of Guizhi, 14 parts of stamens, and 6 parts of Peilan 10 parts of Daqingye, 11 parts of Paojiang, 10 parts of lotus pod, 6 parts of Wulingzhi, 8 parts of Zizhucao, 4 parts of Puhuang (charcoal), 10 parts of sea octopus, 35 parts of polyglycolic acid, 13-14 parts of chitin, 5 parts of crosslinking agent, 3 parts of stabilizer, 2 parts of antibacterial agent.

[0043] A preparation method of polyglycolic acid anti-infection surgical suture is:

[0044] (1) Remove impurities and wash the rescue Bing, Changshan and Daqingye, add rice wine and mix well, put it in a pot and steam it thoroughly, take it out, let it cool, chop it up, stir-fry it until the surface is dry, take it out, and dry it in the air;

[0045] (2) Crack the stamen into small pieces, put it into...

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Abstract

The invention discloses a polyglycolic acid anti-infection surgical suture which is mainly prepared from, by mass, 4-10 parts of chrysanthemum, 8-15 parts of ilex rotunda thunb, 7-14 parts of antifebrile dichroa, 6-11 parts of cassia twigs, 12-18 parts of marmor serpentinatum, 4-10 parts of herba eupatorii, 9-13 parts of folium isatidis, 10-14 parts of baked ginger, 8-15 parts of receptaculum nelumbinis, 5-9 parts of trogopterus dung, 7-12 parts of purple beads grass, 3-7 parts of cattail pollen (carbon), 9-12 parts of cuttlebone, 30-50parts of polyglycolic acid, 12-15 parts of chitin, 3-9 parts of cross-linking agents, 2-6 parts of stabilizer and 1-4 parts of antibacterial agents. According to the polyglycolic acid anti-infection surgical suture, the Chinese native medicine effective components and a suture preparation process are scientifically combined, operation is simple, the prepared surgical suture is good in flexibility, high in tensile strength, good in biocompatibility, capable of being degraded and absorbed in a human body, free of toxic and side effects, resistant to infection and capable of promoting wound healing, and the suture is not needed to be taken out.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a polyglycolic acid anti-infection surgical suture and its preparation method. Background technique [0002] Surgical sutures are commonly used biological textiles, which are widely used in various surgical operations to suture wounds and connect tissues, and are extremely important medical materials. Surgical sutures are sewn into the human body and maintain long-term or lasting contact with human tissues, organs and blood. According to their behavior in living tissues, they can be divided into biodegradable and biodegradable absorbable. Among them, biodegradable and absorbable ones are of great significance to the repair and reconstruction of tissues and organs. It disappears by degrading into substances that can be absorbed by the human body, avoiding some adverse effects such as rejection in the body and non-infectious inflammation. As a natural absorbable suture material, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/12A61L17/10A61K36/9068A61P31/04A61K35/24A61K35/618A61K33/10
Inventor 不公告发明人
Owner 钊桂英
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