Coherent self-adaptive optical aberration correction system

Abstract

The invention discloses a coherent self-adaptive optical aberration correction system. The system comprises a laser light source, a reflective mirror, a spatial light modulator, and a neutral density filter, a half-wave plate and a beam expanding lens that are sequentially disposed in an incident light path of the reflective mirror. The reflected light of the reflective mirror serves as incident light of the spatial light modulator, and an angle between the incident light and the reflected light of the spatial light modulator is controlled by means of the reflective mirror. The control over coherent emphasis and coherent weakening of two light beams, regulation and control on the phase position of one of the two light beams can be achieved, so aberration correction of a microscopic system is achieved. A reference light source needs not to be implanted in sample, and the aberration correction speed is fast, so the system is quite suitable for deep aberration correction imaging of an in vivo sample.

Description

technical field [0001] The invention belongs to the technical field of optical microscopic imaging, and more specifically relates to a coherent adaptive optical aberration correction system. Background technique [0002] We know that when performing in vivo imaging of biological cells, the system often introduces large aberrations due to the unevenness of the surface of the biological sample and the inhomogeneity of the refractive index distribution inside the sample, which eventually leads to poor image quality. At present, the existing aberration correction method is adaptive optics aberration correction, which is a traditional aberration correction method. It needs to implant a reference light source (usually a fluorescent material such as fluorescent beads) in a biological sample. Biological samples are more harmful and limit the application of this method to in vivo imaging. Contents of the invention [0003] Aiming at the defects of the prior art, the present invent...

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Problems solved by technology

[0003] Aiming at the defects of the prior art, the present invention provides a coherent adaptive optical aberration correction system, the purpose of which is to realize the coherence enhancement and coherence of the two beams of coherent light by adjusting the phase of a beam of light in the two beams of coherent light. Attenuated manipulation, thus realizing the aberration correction of the microscopic system; aiming to solve the technical problem of poor imaging quality of deep tissue cells in vivo

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