Correction method for blood glucose level of blood sample

A calibration method and blood sample technology, applied in the field of blood glucose value calibration, can solve the problems of time-consuming preparation process and detection process, insufficient patient accuracy, etc., and achieve the effect of high accuracy and eliminating the need for devices

Active Publication Date: 2018-03-02
DELBIO
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, there are some limitations in the field of measuring analytes by electrochemical methods, such as the need to use both direct current and alternating current in the detection process
In addition, the overly complicated structure of the test piece makes the preparation process and the detection process relatively time-consuming. In addition, the existing methods of detecting the hematocrit ratio and compensating the blood sugar value will be affected by the concentration of glucose or interfering substances in the blood sample. Errors, resulting in Accuracy of self-measurement by patients is still insufficient

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Correction method for blood glucose level of blood sample
  • Correction method for blood glucose level of blood sample
  • Correction method for blood glucose level of blood sample

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0076] Experimental example 1: Obtain the linear relationship between the hematocrit index and the hematocrit

[0077]Prepare the same batch of blood glucose test strips and blood samples from the same blood specimen, adjust the blood glucose concentration of the blood samples to 175mg / dL, and process three groups of blood glucose test strips with hematocrit (%) of 9%, 42% and 71% respectively. Blood samples are tested.

[0078] The above-mentioned three groups of blood samples whose hematocrit (%) were 9%, 42% and 71% were processed with two experimental conditions, one of which was only processed by a high-voltage section to measure the hematocrit index (code name: Group A), and the other group was treated with the calibration method of the present invention (code name: Group B), and the instrument used was DELBiometer or CHInstrument potentiostat. Specifically, in group A, at room temperature (25±2°C, RH=60±5%), DELBio test strips were applied to blood samples with various...

experiment example 2

[0080] Experimental example 2: Linear regression distribution relationship of hematocrit ratio index at different glucose concentrations

[0081] Prepare the same batch of blood glucose test strips and blood samples from the same blood sample, adjust the blood glucose concentration of the blood sample to 175mg / dL, and process five groups of glucose concentrations of 50, 175, 300, 470 and 600 (mg / dL) ) blood samples for testing.

[0082] The above five groups of blood samples with glucose concentrations of 50, 175, 300, 470 and 600 (mg / dL) were processed under two experimental conditions (ie, the voltage application conditions of the above-mentioned groups A and B). Depend on Figure 4 It can be seen that the hematocrit index obtained in group B is less affected by the glucose concentration than that in group A, that is, the hematocrit index obtained in group B is affected by the blood glucose concentration in the glucose concentration range of 40-600mg / dL small. In addition...

experiment example 3

[0083] Experimental Example 3: Using the hematocrit ratio to feed back the deviation ratio before and after the blood glucose level

[0084] Prepare the same batch of blood glucose test strips and blood samples from the same blood specimen, adjust the blood glucose concentration of the blood samples to 175mg / dL, and process three groups of blood glucose test strips with hematocrit (%) of 9%, 42% and 71% respectively. Blood samples are tested.

[0085] The above five groups of blood samples with hematocrit (%) of 9%, 42% and 71% were processed under three experimental conditions (ie no feedback group, feedback group A and feedback group B). Among them, the non-feedback group is the blood glucose value obtained by applying a first voltage to blood samples with different hematocrits (9%, 42% and 71%) on the DELBio test strip at room temperature. In group A with feedback, at room temperature (25±2°C, RH=60±5%), a DELBio test strip was applied to blood samples of various hematocri...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A method for correcting the blood sugar level of a blood sample, comprising the following steps: applying a first voltage to a blood sample to obtain a first blood sugar value; applying a second voltage to the blood sample to obtain a second blood sugar value; Applying a third voltage to the blood sample to obtain a hematocrit index of the blood sample; and processing the hematocrit index and correcting the second blood glucose value. Wherein, the third voltage is greater than the first voltage. The present invention can obtain the sensing current corresponding to the blood sugar value and a hematocrit index corresponding to the blood sample by applying at least three-stage voltages within specific ranges to the blood sample, and further correct the blood glucose concentration according to the hematocrit index compensate.

Description

technical field [0001] The invention relates to a method for correcting the blood sugar level of a blood sample, in particular to a method for correcting the blood sugar level of a blood sample with at least three-stage voltage applied. Background technique [0002] With the advancement of science and technology and the change of human living habits, the field of home care has been paid more and more attention. In addition to being able to grasp the real-time condition of patients at any time, many test items that originally had to be carried out in hospitals have been developed to home measurement. Measurement is a common detection item, and measuring blood glucose concentration is an important step in effective monitoring and treatment of diabetes. [0003] However, current household or portable blood glucose testing machines often have a large error value, which is a shortcoming and problem criticized by users. As for the reason, the most influential factor is the hemato...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/416
Inventor 蔡宗轩银解语周忆安
Owner DELBIO
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap