Pharmaceutical composition for treating gout and preparation method thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for the treatment of gout and its preparation, and can solve problems such as large side effects, impact of follow-up treatment of gout patients, and irrationality

Inactive Publication Date: 2015-12-23
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the influence of various factors, the age of gout patients is becoming younger at present, and due to untimely or unreasonable drug treatment, it can also lead to chronicity of acute gout or the development of tolerance gout, which will have a great impact on the follow-up treatment of gout patients. bad influence
Current clinical studies have shown that most of the drugs for the treatment of gout have good curative effect, but have relatively large side effects, so finding new drugs with less toxic and side effects and blocking the occurrence of gout from the source is the current research direction

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the pharmaceutical composition for the treatment of gout and preparation method thereof

[0038] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of gout are:

[0039] 9 parts by weight of deacetylated argentin, 60 parts by weight of japonica, 45 parts by weight of oleuropein, 3 parts by weight of swertigin, 1.5 parts by weight of podocarpus resinol;

[0040] Preparation:

[0041](1) According to the ratio of the raw materials, take the stigmata japonica and deacetylated argentinin, mix them well, first use ethanol with a concentration of 60% by weight as a solvent, and extract them by warm soaking at 45°C. The number of extractions is 5 times, each time The extraction time is 2 hours, and the amount of solvent used each time is 18 times of the total weight of the medicinal materials of japonica japonica and deacetylarthiradigenin, and is filtered to obtain the medicinal residue A and the extract, a...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for the treatment of gout and preparation method thereof

[0045] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of gout are:

[0046] 10 parts by weight of deacetylated argentin, 50 parts by weight of japonica, 50 parts by weight of wall coat, 4 parts by weight of oleuropein, 4 parts by weight of swertigin, 1 part by weight of podocarpine resinol;

[0047] Preparation:

[0048] (1) According to the ratio of the raw materials, take the stigmata japonica and deacetylated argentinin, mix them well, first use ethanol with a concentration of 60% by weight as a solvent, and extract them by warm soaking at 45°C. The number of extractions is 5 times, each time The extraction time is 2 hours, and the amount of solvent used each time is 18 times of the total weight of the medicinal materials of japonica japonica and deacetylarthiradigenin, and is filtered to obtain the medici...

Embodiment 3

[0051] Embodiment 3: the pharmaceutical composition for the treatment of gout and preparation method thereof

[0052] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of gout are:

[0053] 8 parts by weight of deacetylated argentin, 70 parts by weight of styloba, 40 parts by weight of oleuropein, 2 parts by weight of swertigin, 2 parts by weight of podocarpus resinol;

[0054] Preparation:

[0055] (1) According to the ratio of the raw materials, take the stigmata japonica and deacetylated argentinin, mix them well, first use ethanol with a concentration of 60% by weight as a solvent, and extract them by warm soaking at 45°C. The number of extractions is 5 times, each time The extraction time is 2 hours, and the amount of solvent used each time is 18 times of the total weight of the medicinal materials of japonica japonica and deacetylarthiradigenin, and is filtered to obtain the medicinal residue A and the extract, and...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating gout and a preparation method thereof. The pharmaceutical composition is prepared by proportioning the following raw materials: deacylmetaplexigenin, lomatogonium carinthiacum, thallus theloschestei flavicani, oleuropein, sweroside and matairesinol, and the pharmaceutical composition can be prepared into various dosage forms according to conventional preparation processes, and the curative effect of treating gout is obvious.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating gout and a preparation method thereof. Background technique [0002] Gout is a group of heterogeneous diseases caused by long-term purine metabolism disorder and elevated blood uric acid causing tissue damage. The clinical features are: hyperuricemia, recurrent attacks of characteristic acute arthritis, sodium urate crystals can be found in the white blood cells of the synovial fluid of the joints, tophi formation, and severe cases can lead to joint movement disorders and deformities, renal uric acid stones and / or Gouty nephropathy. With the change of living habits, the incidence of gout is increasing year by year. Studies have shown that before the 1980s, the incidence of gout in my country was very small. The survey results in 1980 showed that hyperuricemia in Beijing, Shanghai, and Guangzhou The preva...

Claims

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Application Information

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IPC IPC(8): A61K36/51A61P19/06A61K31/569A61K31/7048A61K31/365
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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