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A kind of antibacterial surgical suture thread and preparation method thereof

A technology of surgical suture and triclosan, which is applied in the field of antibacterial surgical suture and its preparation, can solve the problems of incomplete absorption, etc., and achieve the effect of long maintenance time, long tension and good antibacterial effect

Active Publication Date: 2017-11-14
淮安市平安医用设备有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If it is due to the production process, there are other non-degradable chemical components, the absorption is not complete

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] An antibacterial surgical suture, mainly made of the following raw materials according to the ratio of parts by mass: 25 parts of polypropylene resin, 2 parts of polyglycolide, 6 parts of polylactide, 4 parts of polyglycolide lactide, three parts Chlorogen 8 parts, double distilled water 35 parts.

[0024] A preparation method for antibacterial surgical sutures, comprising the following steps:

[0025] (1) dissolving triclosan in double-distilled water to prepare base liquid, the mass concentration of triclosan is 0.1%;

[0026] (2) Polypropylene resin, polyglycolide, polylactide and polyglycolide lactide are placed in a reaction kettle, and a melt is made at a temperature of 320°C and a pressure of 1.5MPa, and the Dried and pulverized into powder, the particle size is 1200 mesh;

[0027] (3) Add the powder obtained in step (2) into the base liquid in step (1), stir and evaporate to a viscous paste at a temperature of 104°C and a rotation speed of 900 rpm;

[0028] (...

Embodiment 2

[0029] An antibacterial surgical suture, mainly made of the following raw materials according to the ratio of parts by mass: 38 parts of polypropylene resin, 9 parts of polyglycolide, 16 parts of polylactide, 12 parts of polyglycolide lactide, three Chlorogen 15 parts, double distilled water 48 parts.

[0030] A preparation method for antibacterial surgical sutures, comprising the following steps:

[0031] (1) dissolving triclosan in double distilled water to prepare a base liquid, the mass concentration of triclosan is 0.8%;

[0032] (2) Polypropylene resin, polyglycolide, polylactide and polyglycolide lactide are placed in a reaction kettle, and a melt is made at a temperature of 380°C and a pressure of 2.4MPa, and the Dried and pulverized into powder, the particle size is 1500 mesh;

[0033] (3) Add the powder obtained in step (2) into the base liquid in step (1), stir and evaporate to a viscous paste at a temperature of 116°C and a rotation speed of 1300 rpm;

[0034] (...

Embodiment 3

[0035] An antibacterial surgical suture, mainly made of the following raw materials according to the ratio of parts by mass: 40 parts of polypropylene resin, 12 parts of polyglycolide, 18 parts of polylactide, 15 parts of polyglycolide lactide, three Chlorogen 17 parts, double distilled water 50 parts.

[0036] A preparation method for antibacterial surgical sutures, comprising the following steps:

[0037] (1) Dissolving triclosan in double-distilled water to prepare a base solution, the mass concentration of triclosan is 0.9%;

[0038] (2) Polypropylene resin, polyglycolide, polylactide and polyglycolide lactide are placed in a reaction kettle, and a melt is made at a temperature of 390°C and a pressure of 2.7MPa, and the Dried and pulverized into powder, the particle size is 1600 mesh;

[0039] (3) Add the powder obtained in step (2) into the base liquid in step (1), stir and evaporate to a viscous paste at a temperature of 113°C and a rotation speed of 1300 rpm;

[0040...

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PUM

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Abstract

The invention discloses an anti-bacterial operation suture line and a method for preparing the same. The anti-bacterial operation suture line is mainly prepared from, by mass parts, 25-45 parts of polypropylene resin, 2-14 parts of polyglycolide, 6-20 parts of polylactide, 4-16 parts of poly glycolide-co-lactide, 8-20 parts of triclosan and 35-55 parts of double distilled water. Compared with the prior art, the anti-bacterial operation suture line has the advantages that the anti-bacterial operation suture line is good in anti-bacterial effect and can effectively prevent operative wound infection; and the tension maintenance time of the anti-bacterial operation suture line is long, and complete healing of operation wounds can be guaranteed.

Description

technical field [0001] The invention relates to the field of medical biomaterials, in particular to an antibacterial surgical suture and a preparation method thereof. Background technique [0002] Surgical sutures refer to special threads used for suturing hemostasis and tissue suturing in surgical operations or in trauma treatment. Generally, it can be divided into two categories: absorbable thread and non-absorbable thread: antibacterial surgical suture can be divided into catgut, chemical synthetic thread, and pure natural collagen suture according to the material and degree of absorption. [0003] Sheep catgut is made from healthy animal sheep intestines and contains collagen, so there is no need to remove the sutures after suturing. There are two types of medical gut: common gut and chrome gut, both of which can be absorbed. The length of time required for absorption depends on the thickness of the gut and the condition of the tissue. Generally, it can be absorbed wit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L17/12
Inventor 吕渐成严琨徐真蕊
Owner 淮安市平安医用设备有限公司
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