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Grinding device for biological tissue

A biological tissue and grinding device technology, applied in the preparation of test samples, etc., can solve the problems of single sample size, long grinding time, easy slipping, etc., to meet the experimental requirements, reduce the cost of the test, and the effect of low cost

Inactive Publication Date: 2015-05-06
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The homogenizer is a relatively primitive homogenizing device. Although the structure is simple, it is difficult to control the balance during operation, and it is easy to be damaged; Too long, single sample size
Although the electric bead mill has a large amount of samples each time, the noise is large, and the structure of the internal tissue fixer has many deficiencies. One is that the tissue fixation frame is thin, and the grinding beads in the centrifuge tube are easy to break the centrifuge tube; two. The centrifuge tube is directly connected to the air, and the heat generated by the centrifuge tube cannot be absorbed in time, which reduces the extraction effect; the third is that the cover part lacks a shock-absorbing layer, which is easy to slip off

Method used

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  • Grinding device for biological tissue
  • Grinding device for biological tissue
  • Grinding device for biological tissue

Examples

Experimental program
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Effect test

Embodiment Construction

[0014] refer to figure 1 . A grinding device for biological tissue, comprising a grinding table 3, an electric device (a motor 6 and a gearbox 7) is provided in its left half, a control panel 8 is installed in the front, and the grinding work is controlled by an electronic control circuit time and speed. The gearbox 7 is connected to the wheel disc 10 through a vertical transmission shaft 9, and a crank connecting rod is provided on the wheel disc to connect a grinder 1 located on the right half of the grinding table, and the grinder is provided with a dovetail groove ( figure 2 ) is matched with the guide rail 2 on the grinding table. Driven by the drive shaft, the wheel disc 10 converts the circular motion into the linear motion of the end of the connecting rod through the crank connecting rod mechanism, and drives the grinder to reciprocate left and right along the guide rail. There is a drawer 4 in the grinding table below the grinder, in which an ice box is arranged to ...

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Abstract

The invention discloses a grinding device for a biological tissue. The grinding device comprises a grinding table with a mechanical transmission case, wherein the grinding table is provided with a grinder, the grinder comprises a pair of base and upper cover, which are identical in shape and size, a plurality of concaved grinding cavities which are regularly arranged are formed in the upper surface of the base, each grinding cavity is in a semicircular ball-socket shape or a semi-elliptic ball-socket shape, and a circular grinding ball is arranged in each grinding cavity; a plurality of concave cavities with quantity identical to that of the grinding cavities of the base are formed in the upper surface of the upper cover, the concave cavities correspond to the grinding cavities of the base in position distribution, when the upper cover is turned to be connected with the base, the concave cavities of the upper over and the corresponding grinding cavities of the base are closed to form a plurality of circular spherical or elliptical spherical closed spaces, the biological tissue and the grinding balls are wrapped by the closed spaces, after the base and the upper cover are fixed by utilizing a clamp, the base is connected to the upper surface of the grinding table through a sliding part, and the upper cover is connected with a drive device in the mechanical transmission case through a crank linkage mechanism; a drawer for storing an ice box is arranged in the grinding table below the grinder.

Description

technical field [0001] The invention relates to a molecular biology method for grinding animal samples (heart, liver, lung, muscle, intestinal tract, fur, bones, etc.) and plant samples (rice, corn, wheat, beans, peanuts, etc.) to make uniform tissue Slurry, a biological tissue grinding device for RNA, DNA or protein extraction. . Background technique [0002] At present, understanding life phenomena at the molecular level has become the main direction of the development of modern biology. To study biological macromolecules, we must first obtain highly purified and biologically active target substances. The preparation of biological macromolecules involves various technologies such as physics, chemistry and biology, and requires a scientific process. Microorganisms, plants and animals can be used as raw materials for the preparation of biological macromolecules, and the selected materials are mainly determined according to the experimental purpose. For the preparation of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28
Inventor 陈宝莹颜林枫南海燕崔光彬方伟赵欣张轩李静周程沛于军张学策铁茹王田于春英
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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