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Cell analyzer, erythrocyte agglutination warning method and erythrocyte agglutination warning system of the cell analyzer

A technology of red blood cell agglutination and alarm system, which is applied in the field of cell analyzer and its red blood cell agglutination alarm, which can solve the problems of low accuracy and failure to give RBC agglutination alarm, and achieve the effect of improving the accuracy of the alarm

Active Publication Date: 2015-04-15
SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the sample is a hypochromic sample, the MCHC value when the sample does not agglutinate is lower than the normal reference range. When the sample has RBC agglutination, the MCHC value rises, but it is still within the reference range of a healthy person. At this time, it will not be given RBC agglutination alarm; in addition, for some hyperpigmented samples, the MCHC value itself is higher than the reference range of healthy people, and it is easy to be judged as a mismatch between RBC and HGB, so it is falsely alarmed as RBC agglutination
[0004] Therefore, the traditional alarm method has the disadvantage of low accuracy

Method used

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  • Cell analyzer, erythrocyte agglutination warning method and erythrocyte agglutination warning system of the cell analyzer
  • Cell analyzer, erythrocyte agglutination warning method and erythrocyte agglutination warning system of the cell analyzer

Examples

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Embodiment 1

[0075] Example 1: A normal sample whose red blood cell count is 4.59×10 12 / L, using the erythrocyte agglutination alarm method analysis in the present invention, the value of the erythrocyte agglutination amount thus obtained is 0.0053×10 12 / L, less than the preset quantity threshold, no red blood cell agglutination alarm will be given.

Embodiment 2

[0076] Embodiment 2: A case of normal sample, its erythrocyte count value is 4.98 * 10 12 / L, the white blood cell count was 8.40×10 12 / L, using the erythrocyte agglutination alarm method analysis in the present invention, the value of erythrocyte agglutination thus obtained is 0.0085×10 12 / L, the value of the corrected red blood cell agglutination after correction with the white blood cell value is 0.0001×10 12 / L, if the preset quantity threshold is not reached, no red blood cell agglutination alarm will be given.

Embodiment 3

[0077] Example 3: Detect the agglutination sample with low white blood cell content, and the red blood cell count value is 3.64×10 12 / L, using the cell agglutination alarm method analysis in the present invention, the value of the red blood cell agglutination amount thus obtained is 0.0958×10 12 / L, greater than the preset quantity threshold, an RBC agglutination alarm is given.

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Abstract

A cell analyzer, an erythrocyte agglutination warning method and an erythrocyte agglutination warning system of the cell analyzer. The erythrocyte agglutination warning method includes following steps: (1) measuring volume information of cells in a sample; (2) recognizing the cells of which the volume information is larger than a preset volume threshold value to obtain an agglutinated erythrocyte group; (3) counting the number of the cells in the agglutinated erythrocyte group to obtain an agglutinated erythrocyte amount; (4) determining whether the agglutinated erythrocyte amount is large than a preset number threshold value, and if the agglutinated erythrocyte amount is large than the preset number threshold value, carrying out erythrocyte agglutination warning. Determination on the content of certain components in the cells is unnecessary since the agglutinated erythrocyte is recognized directly according to the volume of the cells, so that compared with a conventional erythrocyte agglutination warning method, the method can improve a warning accuracy and is simple, convenient and quick.

Description

technical field [0001] The invention relates to the technical field of medical detection, in particular to a cell analyzer and a red blood cell agglutination alarm method and system thereof. Background technique [0002] At present, medical particle analyzers have been widely used in the field of medical testing. For example, blood cell analyzers have become an important means of replacing microscopic examinations for blood routine analysis. Take the measurement of red blood cells as an example. Under normal circumstances, red blood cells are evenly distributed in the blood. However, when the sample has defects such as abnormal cold agglutinin content or the blood collection process is not standardized, the red blood cells evenly suspended in the blood may aggregate into clumps, resulting in red blood cells. of agglutination. Red blood cell agglutination will interfere with the measurement results of the hematology analyzer, and at the same time, it is necessary to pay atte...

Claims

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Application Information

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IPC IPC(8): G01N15/05
Inventor 叶波王官振祁欢
Owner SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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