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Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof

A technology for increasing bone density and composition. It can be used in medical preparations containing active ingredients, bone diseases, drug combinations, etc. It can solve the problems of osteoarthritis and osteoporosis, and relieve osteoarthritis and Bone and joint pain, the effect of promoting absorption and deposition, increasing bone density

Inactive Publication Date: 2014-12-10
哈药集团制药六厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a composition that increases bone density and improves bone and joint functions, which solves the problem that middle-aged and elderly people are prone to osteoporosis and often accompanied by osteoarthritis

Method used

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  • Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof
  • Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof
  • Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof

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Experimental program
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Effect test

preparation example Construction

[0026] The preparation method of composition of the present invention can carry out according to the following steps:

[0027] 1. Preparation of glucosamine and chondroitin sulfate granules: put 1-400 parts of glucosamine, 1-400 parts of chondroitin sulfate and 1-500 parts of excipients into a wet mixing granulator and dry mix until evenly mixed. Add appropriate wetting agent or binder to granulate, dry and select granules;

[0028] 2. Preparation of calcium particles. 1-400 parts of calcium agent and 1-500 parts of auxiliary materials are placed in a wet mixing granulator and dry-mixed until uniformly mixed, adding an appropriate wetting agent or binder to granulate, drying, and selecting granules.

[0029] 3. Mixing: Weigh glucosamine, chondroitin sulfate granules and calcium granules according to the formula, add 0.0001-1 part of vitamin D, 0.0001-1 part of vitamin K, and add 1-500 parts of auxiliary materials, and mix well.

[0030] 4. Tablet.

[0031] 5. Film coating. ...

Embodiment 1

[0064] 1. Glucosamine, Chondroitin Sulfate Granules

[0065]

[0066] 2. Calcium particles

[0067]

[0068] 3. Additional raw and auxiliary materials

[0069]

[0070] Take the above-mentioned raw and auxiliary materials, granulate, compress into tablets, and coat according to the wet granulation process.

Embodiment 2

[0071] Embodiment 2: the preparation of this composition tablet:

[0072]

[0073]

[0074] Take the above-mentioned raw and auxiliary materials, granulate, compress into tablets, and coat according to the wet granulation process.

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Abstract

The invention discloses a composition capable of increasing bone density and improving functions of skeletons and joints and a preparation method thereof. The composition capable of increasing the bone density and improving the functions of the skeletons and joints comprises the following main components in parts by mass: 1-400 parts of glucosamine, 1-400 parts of chondroitin sulfate, 1-400 parts of calcium medicinal preparation, 0.0001-1 part of vitamin D and 0.0001-1 part of vitamin K. The composition capable of increasing the bone density and improving the functions of the skeletons and joints has the beneficial effects that calcium is supplemented for young and old patients suffering from osteoporosis, absorption and deposition of calcium in skeleton are promoted, the bone density is effectively increased, and syndromes such as osteoarthritis and bone and arthrosis pain are also alleviated.

Description

technical field [0001] The invention belongs to the technical field of health products, and relates to a composition capable of increasing bone density and improving bone and joint functions and a preparation method thereof. Background technique [0002] Osteoporosis is a metabolic bone disease characterized by loss of bone mass, which can eventually lead to fractures. Osteoporosis is often judged by bone density as the gold standard. Bone density can gradually decrease with age. Osteoporosis has become one of the common diseases of middle-aged and elderly people, seriously affecting the health and quality of life of middle-aged and elderly people. The prevalence of osteoporosis in my country is 16.1%, and it shows a rising trend with age. Osteoporosis and the accompanying fragility fractures will have a serious impact on the lives of middle-aged and elderly people, and the high cost of treatment will also bring a heavy economic burden to the society. Prevention and improve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/737A61K33/10A61K33/06A61K33/42A61K38/00A61P19/10A61P19/08A61P19/02A61P3/02A61K31/7008A61K31/592A61K31/593A61K31/122A61K31/05A61K31/194A61K31/191A61K31/19
Inventor 芦传有夏丽文李桂红
Owner 哈药集团制药六厂
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