Preparation method of traditional Chinese medicine granules, traditional Chinese medicine granules prepared by same and use of traditional Chinese medicine granules

A technology of traditional Chinese medicine granules and medicinal residues, which can be applied to pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., and can solve problems such as poor taste, large dosage, and inconvenience to carry.

Active Publication Date: 2014-12-03
BEIJING HANDIAN PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The above method is only a simple preparation method of traditional Chinese medicine decoction, and does not consider how to fully extract the active ingredients in the medicine, which brings about the problems of large dosage, poor taste, inconvenient to carry, and not suitable for long-term storage

Method used

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  • Preparation method of traditional Chinese medicine granules, traditional Chinese medicine granules prepared by same and use of traditional Chinese medicine granules
  • Preparation method of traditional Chinese medicine granules, traditional Chinese medicine granules prepared by same and use of traditional Chinese medicine granules
  • Preparation method of traditional Chinese medicine granules, traditional Chinese medicine granules prepared by same and use of traditional Chinese medicine granules

Examples

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Comparison scheme
Effect test

Embodiment 1

[0069] Example 1 A preparation method of traditional Chinese medicine granules and the prepared traditional Chinese medicine granules

[0070] API prescription:

[0071] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0072] The concrete steps of described preparation method are as follows:

[0073] (1) Prepare various medicinal materials according to the prescription.

[0074] (2) Add water 10 times the weight of medicinal materials to cinnamon, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 2 times the volume of absolute ethanol to dissolve the volatile oil; take 10 times the volume of the volatile oil β-cyclodextrin, an aqueous solution of β-cyclodextrin made by adding water 25 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol to the aqueous solution of β-cyclodext...

Embodiment 2

[0080] Example 2 A preparation method for extracting traditional Chinese medicine and Chinese medicine extract prepared therefrom

[0081] API prescription:

[0082] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0083] The concrete steps of described preparation method are as follows:

[0084] (1) Prepare various medicinal materials according to the prescription.

[0085] (2) Add water 8 times the weight of the medicinal material to cinnamon, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 1 times the volume of absolute ethanol to dissolve the volatile oil, and take 6 times the volume of β of the volatile oil -Cyclodextrin, add β-cyclodextrin aqueous solution made by adding 15 times the weight of β-cyclodextrin water; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aque...

Embodiment 3

[0091] Example 3 A preparation method of traditional Chinese medicine granules and the prepared traditional Chinese medicine granules

[0092] API prescription:

[0093] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0094] The concrete steps of described preparation method are as follows:

[0095] (1) Prepare various medicinal materials according to the prescription.

[0096] (2) Add cinnamon with 12 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 3 times the volume of absolute ethanol to dissolve the volatile oil, and take 20 times the volume of β of the volatile oil -cyclodextrin, add β-cyclodextrin aqueous solution made of water 40 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous s...

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Abstract

The invention provides a preparation method of traditional Chinese medicine granules, and the traditional Chinese medicine granules prepared by the same. The traditional Chinese medicine granules comprise the following crude drugs in parts by weight: 30-60 parts of astragalus membranaceus, 9-15 parts of glossy privet fruit, 9-30 parts of motherwort, 3-10 parts of smoked plum, 2-9 parts of coptis chinensis, 1-5 parts of cinnamon and 3-9 parts of butterflybush flower. The preparation method comprises the following steps: extracting essential oil from cinnamon, and covering the essential oil by beta-cyclodextrin; extracting astragalus membranaceus, glossy privet fruit and butterflybush flower by use of an ethanol solution I; extracting residues of the smoked plum and the cinnamon, and residues of the astragalus membranaceus, the glossy privet fruit and the butterflybush flower by water; extracting the motherwort and the coptis chinensis by use of an ethanol solution II; mixing each part of extracted extractum; adding pharmaceutical acceptable auxiliary materials, pelletizing, and adding an essential oil inclusion compound; and evenly mixing the materials, so as to obtain the traditional Chinese medicine granules. Compared with the prior art, the preparation method has the advantage of obviously improving the active substance content and pharmacologic action of the traditional Chinese medicine granules.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a method for preparing traditional Chinese medicine granules for diabetic retinopathy, the prepared traditional Chinese medicine granules and uses thereof. Background technique [0002] Diabetic Retinopathy (DR) is one of the serious and common eye complications of diabetes. With the prolongation of the duration of diabetes, the incidence of DR also increased. The incidence of diabetic retinopathy is about 50% in those with a course of more than 8 years. The early symptoms of the disease are not obvious and are easy to be ignored. In the late stage, there is no effective control method, and the disease is lingering and intractable. If the disease is not treated, the consequences are serious, and it is the main cause of adult blindness, with a blinding rate of 8-12%, which has a serious adverse effect on the quality of life of the affected population. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K9/16A61K47/48A61P3/10A61P9/10
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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