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Medicament composition for treating rheumatoid arthralgia and hyperostosis and preparation method thereof

A technique for rheumatic joint pain and bone hyperplasia, which is applied to the pharmaceutical composition for bone hyperplasia and its preparation, and the field of treating rheumatic joint pain, and can solve the problems of not being able to fundamentally solve the problem of onset, increasing gastrointestinal ulcers and bleeding, etc.

Active Publication Date: 2014-09-10
贵州遵义华源医药保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical observations show that frequent use of NSAIDs has serious side effects and increases complications such as gastrointestinal ulcers and bleeding, and the treatment is mainly symptomatic and cannot fundamentally solve the problem

Method used

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  • Medicament composition for treating rheumatoid arthralgia and hyperostosis and preparation method thereof
  • Medicament composition for treating rheumatoid arthralgia and hyperostosis and preparation method thereof
  • Medicament composition for treating rheumatoid arthralgia and hyperostosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Raw materials: Achyranthes bidentata 35g, Eupatorium 35g, Aconitum 35g, S. chinensis 30g, Herba chinensis 30g, Zanthoxylum bungeanum 30g, Artemisia argyi 30g, Fangfeng 30g, Ligusticum chuanxiong 30g.

[0071] The preparation method is:

[0072] 1), mix the components in proportion, add ethanol with an alcohol concentration of 75% relative to the mass of the mixture which is 3 times, heat and reflux for 2 hours, extract 3 times, combine the extracts, filter to obtain the alcohol extract, the alcohol extract reduces Concentrate under pressure, recover until there is no alcohol smell, and obtain the alcohol extract, which is concentrated under reduced pressure to a relative density of 1.20; the dregs are set aside;

[0073] 2) Add distilled water 5 times the mass of the mixture of the components of the medicine for external use to the dregs, decoct 3 times for 2 hours each time, filter separately, combine the filtrates to obtain a water extract, and concentrate the water e...

Embodiment 2

[0089] Raw materials: Achyranthes bidentata 30kg, Eupatorium 30kg, Aconitum 30kg, S. chinensis 36kg, Herba chinensis 36kg, Zanthoxylum bungeanum 36kg, Artemisia argyi 36kg, Fangfeng 36kg, Ligusticum chuanxiong 36kg.

[0090] Preparation:

[0091] 1), mix the components in proportion, add ethanol with an alcohol concentration of 70% relative to the mass of the mixture twice, heat and reflux for 1 hour, extract twice, combine the extracts, filter to obtain the alcohol extract, and the alcohol extract reduces Concentrate under pressure, recover until there is no alcohol smell, and obtain the alcohol extract, which is concentrated under reduced pressure to a relative density of 1.05; the dregs are set aside;

[0092] 2) Add distilled water with 4 times the weight of the mixture of the components of the external medicine to the dregs, decoct twice for 1 hour each time, filter separately, combine the filtrates to obtain a water extract, and concentrate the water extract under reduce...

Embodiment 3

[0107] Raw materials: Achyranthes bidentata 40kg, Eupatorium 40kg, Aconitum 40kg, Rhizoma 24kg, Grass 24kg, Zanthoxylum bungeanum 24kg, Artemisia argyi 24kg, Fangfeng 24kg, Ligusticum chuanxiong 24kg

[0108] Preparation:

[0109] 1), mix the components in proportion, add ethanol with an alcohol concentration of 4 times relative to the mass of the mixture and be 80% ethanol, heat and reflux for 3 hours, extract 4 times, combine the extracts, filter to obtain the alcohol extract, and the alcohol extract reduces Concentrate under pressure, recover until there is no alcohol smell, and obtain the alcohol extract, which is concentrated under reduced pressure to a relative density of 1.25; the dregs are set aside;

[0110] 2) Add distilled water 4 to 6 times the mass of the mixture composed of the components of the medicine for external use, decoct 4 times, each time for 3 hours, filter separately, combine the filtrates to obtain a water extract, and decompress the water extract Co...

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Abstract

The invention discloses a medicament composition for treating rheumatoid arthralgia and hyperostosis and a preparation method thereof. The medicament composition comprises the following medicinal materials in parts by weight: 30-40 parts of radix achyranthis bidentatae, 30-40 parts of herba lycopi, 30-40 parts of monkshood, 24-36 parts of sargentgloryvine stem, 24-36 parts of lycopodium clavatum, 24-36 parts of pepper, 24-36 parts of folium artemisiae argyi, 24-36 parts of saposhnikovia divaricata, and 24-36 parts of ligusticum wallichii. The medicament composition and the preparation have the effects of invigorating the circulation of blood and eliminating blood stasis, relaxing muscle and relieving pain, dispelling wind and eliminating dampness, and have a simple prescription; long-term study finds that clinically, the medicament composition has curative effects to rheumatoid arthralgia, hematoma, hyperostosis and traumatic injuries, is safe, has no toxic and side effects, is practical and convenient to take, and can be easily taken by patients.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating rheumatic joint pain and hyperosteogeny and a preparation method thereof. Background technique [0002] Rheumatoid arthritis and hyperosteogeny are long-term chronic and obstinate commonly encountered diseases, frequently-occurring diseases, and are relatively common. Once you get sick, you will suffer from the pain for life, you will not be able to work and live normally, and your body and mind will be greatly hurt. The clinical manifestations of rheumatoid arthritis are joint swelling and pain or migratory pain, numbness of limbs, joint deformation, movement obstruction, and some are even permanently disabled, seriously endangering people's health; Chronic joint disease caused by the destruction of articular cartilage, the onset of the disease is slow, without systemic symptoms, mostly middle-aged and elderly pe...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P19/02A61P29/00A61P19/08
Inventor 徐小勇
Owner 贵州遵义华源医药保健品有限公司
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