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CTC blood filtering and dialyzing system

A hemodialysis and blood technology, applied in dialysis systems, blood filtration, suction equipment, etc., can solve the problem of CTC without filtration

Inactive Publication Date: 2014-07-23
王雪霏 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although the current hemodialysis machine can filter human blood, it does not have the function of filtering CTC
Therefore, existing medicine is a blind spot in the direct filtering of CTCs for adjuvant treatment of breast cancer

Method used

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  • CTC blood filtering and dialyzing system
  • CTC blood filtering and dialyzing system
  • CTC blood filtering and dialyzing system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0006] exist figure 1 The arterial blood of patients with breast cancer flows from the human body to the CTC hemodiafiltration system in the direction of the arrow, passes through the heparin pump and blood pump, flows to the core device CTC filter, and then flows through the dialyzer, and returns to the human body from the venous end after simple treatment .

[0007] exist figure 2 , 3 The middle blood flows into the inner layer of the filter from the arterial end, and after being filtered by the biofilm with a pore size of 8 μm in the inner layer of the filter, it flows into the dialyzer through the outlet of the outer layer of the filter.

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Abstract

The invention relates to a blood filtering and dialyzing system capable of filtering and separating CTCs of a human body from circulation blood of the human body. The blood filtering and dialyzing system serves as an adjuvant therapy device and is suitable for breast cancer patients with the positive CTCs. The blood filtering and dialyzing system is characterized in that in a pipe channel of an existing blood filtering and dialyzing device, a filter composed of biological membranes 8 micrometers in hole diameter is additionally arranged. The filter is a cylinder and taper double-layer barrel, and the blood dialyzing instrument artery end is communicated with an inner layer, wherein the inlet radius is r, and the inner layer is composed of biological membranes 8 micrometers in hole diameter; the blood dialyzing instrument vein end is communicated with an outer layer, and the outer layer is made of medical plastic. According to the filter, the heights of a cylinder in the inner layer and a cylinder in the outer layer are equal, the length is controllable in the scope ranging from 10 cm to 20 cm, the inner diameter is 4.472 r, the outer diameter is 4.48 r, the height of an inner taper is 4.472 r, the height of an outer tapper is 4.48 r, and the membrane hole distribution density is 100000 / cm<2>.

Description

technical field [0001] The invention relates to a device for filtering and separating CTC from circulating blood of a human body. As an adjuvant therapy device, it is suitable for breast cancer patients with positive CTC (circulating blood tumor cells). Background technique [0002] Breast cancer has been considered as a systemic disease, that is, the systemic spread of tumor cells can occur in the early stage, and distant metastasis is the main cause of treatment failure and death in breast cancer patients. Tumor cells that disseminate in the blood, known as CTCs (circulating tumor cells), are thought to be associated with recurrence and metastasis in breast cancer patients. However, current methods to remove CTCs are limited to chemotherapy. But for those chemotherapy-resistant CTCs, they can also reach distant organs and eventually lead to recurrence and metastasis. Most patients still have CTCs in peripheral blood after surgery and chemotherapy. However, the current ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/16
CPCA61M1/34A61M1/3633
Inventor 王雪霏孙强
Owner 王雪霏
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