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Application of traditional Chinese medicine composition in preparation of medicine for treating depression

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as large side effects and patient distress, and achieve the effect of no side effects and good curative effect

Active Publication Date: 2014-07-23
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] These drugs treat depression, have serious side effects, and cause other problems for patients

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating depression
  • Application of traditional Chinese medicine composition in preparation of medicine for treating depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Embodiment 1: the preparation of medicine capsule of the present invention

[0054] Prescription: Astragalus 450g, Aconite 112.5g, Ginseng 225g, Salvia miltiorrhiza 225g, Tinglizi 150g

[0055] Xiangjia skin 180g Alisma 225g safflower 90g Polygonatum 75g Chenpi 75g Guizhi 90g

[0056] Preparation:

[0057] (1) Reflux extract astragalus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the above prescription plus 8 times the amount of 70% ethanol for 2 times, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter After passing through, the filtrate decompresses and reclaims ethanol, and concentrates to a clear paste with a relative density of 1.25 (60°C thermal measurement), for subsequent use;

[0058] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription, filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the residue and decoct ...

Embodiment 2

[0061] Embodiment 2: the preparation of pharmaceutical tablet of the present invention

[0062] Prescription: Astragalus 150g, Aconite 40g, Codonopsis 225g, Salvia miltiorrhiza 225g, Tinglizi 50g

[0063] Nanwujiapi 180g Alisma 75g Polygonatum 75g Guizhi 30g Safflower 90g Chenpi 25g

[0064] Preparation:

[0065] (1) Weigh Astragalus, Tinglizi, Alisma, Codonopsis, and Acanthopanax bark according to the proportion, add 8 times the amount of 70% ethanol to reflux and extract twice, the first time is 3 hours, the second time is 2 hours, combined extraction liquid, filtered, and the filtrate was decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.25 (60°C thermal measurement), and set aside;

[0066] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription amount, filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the residue and decoct for 1 hou...

Embodiment 3

[0069] Embodiment 3: the preparation of medicament oral liquid of the present invention

[0070] Prescription: Astragalus 250g, Aconite 112.5g, Codonopsis 200g, Salvia miltiorrhiza 120g, Tinglizi 135g

[0071] Xiangjiapi 150g Alisma 200g Polygonatum 60g Guizhi 75g Safflower 75g Chenpi 60g

[0072] Preparation:

[0073] (1) Extract Astragalus, Tinglizi, Alisma, Codonopsis, and Xiangjiapi according to the above prescription and add 8 times the amount of 70% ethanol to reflux twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter After passing through, the filtrate decompresses and reclaims ethanol, and concentrates to a clear paste with a relative density of 1.28 (60°C thermal measurement), for subsequent use;

[0074] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription, filter the aqueous solution after oil extraction, and set aside, add 6 times the amount of water to the residue and ...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for treating depression, and belongs to the field of applications of traditional Chinese medicines. The traditional Chinese medicine composition comprises radix astragali, aconite root, ginseng or radix codonopsitis, red sage root, semen lepidii, cortex periplocae or cortex acanthopanacis, rhizoma alismatis, radix polygonati officinalis, cassia twig, safflower and dried orange peel, and has an antidepressant function. The ginseng can tonify qi, dredge collaterals, benefit qi and calm the nerves. The dried orange peel can smooth the liver, relieve depression, promote qi circulation and remove obstruction in the collaterals. The red sage root and the safflower can promote blood circulation to remove blood stasis and dredge collaterals. The cassia twig can dredge collaterals with warm pungent, warm yang, and promote the flow of qi. By combination of the raw materials, the traditional Chinese medicine composition has functions of regaining smoothness of collaterals, qi and blood circulation, and improving the mood.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine application, and in particular relates to a new application of a traditional Chinese medicine composition. Background technique [0002] Depression is a common mood disorder, which can be caused by various reasons. The main clinical feature is marked and persistent low mood, and the low mood is not commensurate with the situation. In severe cases, suicidal thoughts and behaviors may appear. Most cases have a tendency to relapse, and most of each attack can be relieved, and some may have residual symptoms or become chronic. [0003] Treatment for depression includes medication, psychotherapy, and physical therapy. The current first-line antidepressants include SSRI drugs, such as paroxetine, sertraline, fluoxetine, citalopram, fluvoxamine, etc., commonly known as "five golden flowers", common adverse reactions include nausea, vomiting, Anorexia, constipation, diarrhea, dry mouth, tremo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/48A61P25/24
Inventor 周梦夏秦拢马桂云郑淑艳
Owner HEBEI YILING MEDICINE INST
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