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Use of pistacia chinensis bunge and lance asiabell root extracts in toxicity reduction and efficacy enhancement of cancer chemotherapy

A technology of extract and four-leaf ginseng, applied in the field of natural pharmaceutical compositions, can solve the problems of strong toxic and side effects, no anti-cancer synergistic effect, and empty use range, etc., and achieves good synergy, good anti-vomiting, and good synergy effect of action

Inactive Publication Date: 2014-07-09
刘明
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commonly used antiemetic drugs in clinical practice mainly include histamine, acetylcholine and dopamine receptor antagonists, corticosteroids and cannabinoids, etc., but these drugs have poor curative effect on post-chemotherapy vomiting and strong toxic and side effects, so their application is greatly limited. Antiemetic drugs, such as NK receptor antagonists and 5HT receptor antagonists, have good antiemetic effects, but they are expensive, have no scope of use, and have large toxic and side effects. See anti-cancer synergistic effect, so look forward to the development of natural low-toxic anti-cancer attenuated and synergistic drugs

Method used

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  • Use of pistacia chinensis bunge and lance asiabell root extracts in toxicity reduction and efficacy enhancement of cancer chemotherapy
  • Use of pistacia chinensis bunge and lance asiabell root extracts in toxicity reduction and efficacy enhancement of cancer chemotherapy
  • Use of pistacia chinensis bunge and lance asiabell root extracts in toxicity reduction and efficacy enhancement of cancer chemotherapy

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Experimental program
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Embodiment approach

[0032] The first step: preparation of various extracts

[0033] (1) Preparation of Kaimu extract

[0034] Take fresh branches and leaves of Kaimu (1:1), dry, crush, sieve, soak in 3-10 times ethanol for 12 hours, filter to get the clarified liquid, centrifuge (3000rpm) for 15 minutes, separate the supernatant, distill to remove ethanol, Then dry under reduced pressure to obtain a dry extract, crush and sieve. Add 6 times distilled water to the dregs after extraction, soak, decoct, filter, centrifuge at 3000rpm for 15 minutes, separate the supernatant, dry it under reduced pressure into a dry extract, crush, sieve, combine the two powders to obtain Kaimu extract things.

[0035] (2) Preparation of Ginseng Extract

[0036] Cut fresh ginseng into thin slices, dry, crush, sieve, soak in 6 times distilled water, decoct, filter, add 6 times distilled water to the dregs, soak, decoct, filter in the same way, combine the two filtrates, Centrifuge at 3000 rpm for 15 minutes, separa...

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Abstract

The invention relates to a natural pharmaceutical composition, a preparation method and a use thereof in preparation of a toxicity-reducing efficacy-enhancing drug in cancer chemotherapy. The natural pharmaceutical composition is formed from a pistacia chinensis bunge water decoction concentrated extract and a lance asiabell root water decoction concentrated extract according to a ratio of 1:1-20. The composition has a quite good curative effect on emesis and other toxic and side effects caused by the cancer chemotherapy, and can simultaneously play a role in inhibiting tumor.

Description

technical field [0001] The present invention relates to a natural medicinal composition, more specifically to a natural medicinal composition composed of a concentrated decocted extract of Kaimu decoction and a concentrated extract of Ginseng four-leaf decocted in water, a preparation method of the natural medicinal composition and the natural medicinal composition Use of the pharmaceutical composition in the preparation of a medicine for reducing the side effect of vomiting caused by cancer chemotherapy and having a synergistic effect on treating cancer. Background technique [0002] Cancer has become a major killer facing human beings. Although chemotherapy has a certain effect, most patients will experience severe nausea, vomiting and other gastrointestinal reactions after chemotherapy. Frequent vomiting can lead to a large loss of digestive juice, water, electrolytes, acid, etc. Alkaline balance disorder and malnutrition make patients miserable and seriously affect the q...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/344A61P35/00A61P1/08
Inventor 刘明陶美珍李静宋丽阳杨杰岳旺
Owner 刘明
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