Traditional Chinese medicine composition for external use for treating diabetic foot ulcer, preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for external use for treating diabetic foot ulcer. The traditional Chinese medicine composition is prepared from the raw materials in parts by weight: coptis chinensis, pseudo-ginseng, lithospermum, salvia miltiorrhiza, golden cypress, frankincense, myrrh, dragon blood, beewax and calcined gypsum, wherein the raw materials have synergistic effects for recovering the elasticity for the blood vessels by clearing away heat and toxic materials and promoting blood circulation to remove blood stasis; the insufficient blood supply can trend to be normal in a slow process; gene regulation elements and effective active molecules in the traditional Chinese medicine raw materials can enter diseased parts of the blood; in a smooth and steady regulating process, the traditional Chinese medicine composition for external use can be used for repairing damaged tissues and organs of the body by improving liver and kidney mainly, controlling the diabetic pathogenesis step by step, regulating the human body nervous system and promoting blood circulation, playing a coordination and comprehensive treatment role, changing the diabetic pathogenesis radically and recovering the body; the traditional Chinese medicine composition for external use has the effects of removing slough and promoting growth of tissue regeneration, warming the meridians, tonifying qi and activating blood, alleviating phishom limb pain, controlling ulcer surface infection, improving local microcirculation, enhancing bidirectional transfer function of endothelial cells, improving conduction velocity of peripheral nerve and promoting the repair of the tissues and the healing of the wound surfaces.

Description

technical field [0001] The invention relates to a medicine for treating diabetes, in particular to a traditional Chinese medicine composition for external use on diabetic foot ulcer, a preparation method and application thereof. Background technique [0002] Diabetic foot is a common complication of diabetes, which seriously affects the labor ability and quality of life of patients. Diabetic foot ulcer is the main clinical manifestation of diabetic foot, and its amputation rate is 15-20 times that of non-diabetic patients. Studies have shown that the amputation-related all-cause mortality of diabetic patients is more than 5 times higher than that of non-diabetic patients. There are about 92 million diabetic patients in my country, and the incidence of diabetic foot is about 0.9%-14.5%. Diabetic foot has brought a heavy burden to social medical resources. In Western countries, the cost of diabetic foot ulcers is $16,000-27,000 per patient, and the medical cost of amputation...

AI Technical Summary

Problems solved by technology

[0006] (4) Surgical operations and interventional therapy: Arterial stents, balloon dilatation, arterial plaque ablation, arterial plaque atherectomy, artificial vascular bypass, etc. require sophisticated and expensive equipment, heavy trauma, high risk, high cost, and many complications , high mortality, poor patient compliance

[0007] (5) Stem cell therapy: The required equipment is sophisticated and expensive, and due to ethical restrictions, most hospitals cannot carry out it, and the long-term efficacy remains to be seen

However, the evidence-based evidence for the efficacy of these therapies is insufficient and has not been recognized by the international and domestic Western medical circles

The reasons are as follows: (1) The quality of clinical research on the treatment of diabetic foot ulcers with traditional Chinese medicine is not high, and the repeatability of its curative effect is poor, so the credibility has been questioned; In one aspect, the advantages compared with Western medicine are not clear; (3) There is no strict clinical research evidence for the effect of integrated Chinese and Western medicine

[0015] Although the existing traditional Chinese medicines for external application on diabetic feet have a certain curative effect, their onset is slow, the course of treatment is long, and their safety and curative effect are poor.

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