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Drug for treating itchy scalp and dandruff increase

A dandruff and drug technology, applied in the field of medicine, can solve problems such as incomplete absorption, affecting drug efficacy, slow dissolution speed, etc., and achieve the effect of rich foam and good detergency

Active Publication Date: 2014-07-02
JUMPCAN PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, the ciclopirox amine preparation of the prior art has a slow dissolution rate, and when it is used as a skin lotion, its absorption is not complete, which affects the performance of the drug effect

Method used

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  • Drug for treating itchy scalp and dandruff increase
  • Drug for treating itchy scalp and dandruff increase
  • Drug for treating itchy scalp and dandruff increase

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] 1. Prescription

[0033]

[0034] Packing specification: 120g / bottle; 5g / bag

[0035] 2. Production process

[0036] (1) Premixing of auxiliary materials: Take the prescription amount of sodium lauryl sulfate and 10% of the prescription amount of deionized water, add the prescription amount of hair essence, stir until evenly dispersed, and let stand for more than 30 minutes.

[0037] (2) Dosing: Add 80% of the prescribed amount of deionized water to the above premixed excipients, add the prescribed amount of ciclopirox olamine, stir and heat to 60°C, keep stirring to dissolve the main drug completely. Add the prescribed amount of sodium chloride, glycerin, and sodium benzoate, and stir to dissolve them completely. Add 0.3N citric acid solution to adjust the pH value to about 6.6, and add deionized water to the full amount.

[0038] (3) Use a 1.2um filter membrane to keep warm and circulate to filter the sample until there is no obvious visible insoluble foreig...

Embodiment 2

[0042] 1. Prescription

[0043]

[0044] Packing specification: 120g / bottle; 5g / bag

[0045] 2. Production process

[0046] (1) Premixing of auxiliary materials: Take the prescription amount of sodium lauryl sulfate and 10% of the prescription amount of deionized water, add the prescription amount of hair essence, stir until evenly dispersed, and let stand for more than 30 minutes.

[0047] (2) Dosing: Add 80% of the prescribed amount of deionized water to the above premixed excipients, add the prescribed amount of ciclopirox olamine, stir and heat to 60°C, keep stirring to dissolve the main drug completely. Add the prescribed amount of sodium chloride, glycerin, and sodium benzoate, and stir to dissolve them completely. Add 0.3N citric acid solution to adjust the pH value to about 6.6, and add deionized water to the full amount.

[0048] (3) Use a 1.2um filter membrane to keep warm and circulate to filter the sample until there is no obvious visible insoluble foreig...

Embodiment 3

[0052] 1. Prescription

[0053]

[0054] Packing specification: 120g / bottle; 5g / bag

[0055] 2. Production process

[0056] (1) Premixing of auxiliary materials: Take the prescription amount of sodium lauryl sulfate and 10% of the prescription amount of deionized water, add the prescription amount of hair essence, stir until evenly dispersed, and let stand for more than 30 minutes.

[0057](2) Dosing: Add 80% of the prescribed amount of deionized water to the above premixed excipients, add the prescribed amount of ciclopirox olamine, stir and heat to 60°C, keep stirring to dissolve the main drug completely. Add the prescribed amount of sodium chloride, glycerin, and sodium benzoate, and stir to dissolve them completely. Add 0.3N citric acid solution to adjust the pH value to about 6.6, and add deionized water to the full amount.

[0058] (3) Use a 1.2um filter membrane to keep warm and circulate to filter the sample until there is no obvious visible insoluble foreign...

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PUM

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Abstract

The invention relates to a drug for treating itchy scalp and dandruff increase. The drug consists of the following components in parts by weight: 20-50 parts of Ciclopirox olamine, 70-90 parts of lauryl sodium sulfate, 5-20 parts of glycerol, 20-40 parts of sodium chloride, 0.5-2 parts of essence, 0.1-1 part of sodium benzoate, proper amount of citric acid and proper amount of deionized water. The invention further provides a preparation method of ciclopirox olamine hair lotion.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for treating scalp itching and increased dandruff. Background technique [0002] Scalp pityriasis is also called pityriasis simplex. Diffuse off-white chaff-like scales appear on the head, and hair loss may occur over time. [0003] Etiology: The etiology of pityriasis scalp is also multifaceted. In addition to the endocrine and genetic factors already introduced, it may also be related to a round or oval Pityrosporum parasitizing in the outer 2 / 3 of the cuticle. This is a common saprophytic bacterium on normal human scalp and skin. Some scholars have isolated this bacterium from 92% of normal human scalp. Therefore, carriers generally do not necessarily get sick, and only in certain cases do symptoms appear, so it is an opportunistic pathogen. When suffering from scalp pityriasis, this bacterium can aggravate the symptoms. After applying the medicine ...

Claims

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Application Information

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IPC IPC(8): A61K31/4412A61K47/20A61P17/04A61P17/00A61P31/10
Inventor 曹龙祥董自波夏立武邵建国李萍
Owner JUMPCAN PHARMA GRP
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