Application and preparation method of Shuxinning tablets

Abstract

The invention provides an application of Shuxinning tablets in preparing a drug for suppressing the proliferation of murine B16 melanoma cells. A preparation method of the Shuxinning tablets comprises the following steps of: taking twelve medicinal raw materials including 100g of salvia miltiorrhiza, 100g of ligusticum wallichii, 200g of radix paeoniae rubra, 80g of safflower, 80g of angelica sinensis, 80g of radix pseudostellariae, 80g of allium macrostemon, 80g of trichosanthes peel, 60g of polygala tenuifolia, 60g of lignum dalbergiae odoriferae, 60g of rhizoma acori graminei and 60g of liquorice, and preparing the tablets by a conventional method.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an application and preparation method of Shuxinning tablets. Background technique [0002] Shuxinning Tablets are recorded in the Ministry of Health standards. 60g of calamus, 60g of licorice, the above twelve flavors, 50g of chuanxiong and red peony, crushed into fine powder, sieved, and the remaining amount is broken as appropriate; safflower is soaked twice in 75°C warm water for 2 hours each time, combined and soaked liquid, filtered, and the filtrate was concentrated to a thick paste; Xiangxiang was pulverized into coarse powder, and after extracting volatile oil, the residue and other eight flavors such as Salvia miltiorrhiza as well as broken chuanxiong and red peony were boiled twice with water, combined with the decoction, and filtered. After the filtrate was concentrated to a clear paste with a relative density of 1.40 at 65°C, the fin...

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Problems solved by technology

[0002] Shuxinning Tablets are recorded in the Ministry of Health standard. The preparation method is: take 100g of Salvia miltiorrhiza, 100g of Chuanxiong, 200g of red peony, 80g of safflower, 80g of angelica, 80g of heterophylla, 80g of scallion, 80g of melon skin, 60g of Polygala, 60g of Jiangxiang, 60g of Shichangpu, 60g of licorice, 12 flavors above, 50g of each of Chuanxiong and Chishao, crushed into fine powder, sieved, and the rest was crushed as appropriate; safflower was soaked twice in warm water at 75°C for 2 hours each time, combined and soaked liquid, filtered, and the filtrate was concentrated to a thick paste; Jiangxiang was crushed into a coarse powder, and after extracting the volatile oil, the residue was decocted with other eight flavors such as Salvia miltiorrhiza and broken Rhizoma Chuanxiong and Radix Paeoniae Rubra, and decocted twice with water, and the decoction was combined and filtered. After the filtrate is concentrated to a clear paste with a relative density of 1.40 when the filtrate is concentrated to 65°C, add the above-mentioned fine powder and thick paste, mix well, dry, pulverize, sieve to make granules, add balsamic volatile oil, mix well, and press into 800 tablets. Sugar-coated, that is, in the prior art, there is no report on its application in the preparation of drugs for inhibiting the proliferation of B16 mouse melanoma cells

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