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Full-automatic chemiluminescence immune analyzer magnetic bead washing device

A technology of automatic chemistry and luminescence immunity, which is applied in the direction of chemical instruments and methods, cleaning methods and utensils, cleaning methods using liquids, etc., can solve problems such as complex processes, and achieve simple control, less loss of magnetic beads, and clean cleaning effects

Active Publication Date: 2014-02-26
BEIJING LEADMAN BIOCHEM
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a magnetic bead cleaning device for a fully automatic chemiluminescence immunoassay analyzer, which realizes the assembly line cleaning of magnetic beads, cleans cleaner, has less loss of magnetic beads, has a more optimized structure, and is simpler to control. Problems with complex processes in existing technologies

Method used

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  • Full-automatic chemiluminescence immune analyzer magnetic bead washing device
  • Full-automatic chemiluminescence immune analyzer magnetic bead washing device
  • Full-automatic chemiluminescence immune analyzer magnetic bead washing device

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Embodiment Construction

[0017] The present invention will be further described below in conjunction with accompanying drawing.

[0018] A specific embodiment of the present invention in the complete machine structure of a fully automatic chemiluminescence immunoassay analyzer figure 1 and figure 2 As shown, it includes: cuvette rotating disk 4 , elevating needle frame 5 , magnetic bead adsorption device 9 , and a mixing device composed of a mixing friction wheel 10 and a micro-bearing tightening mechanism 11 . The specific structure consists of a cleaning device mounting plate 1, a rotating motor 2, a timing belt 3, a reaction cup rotating disk 4, a lifting needle rack 5 and eight sets of cleaning needles (6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h), Lead screw motor 7, linear slide rail 8, magnet adsorption device 9, mixing friction wheel 10, micro bearing tightening mechanism 11 and other components. The lifting needle frame 5 is driven by the screw motor 7 to move vertically up and down along the linear sl...

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Abstract

A full-automatic chemiluminescence immune analyzer magnetic bead washing device comprises a reaction cup rotation disc, a lifting needle support, a magnetic bead absorbing device and mixing devices. The lifting needle support is driven by a lead screw motor to move vertically along a linear sliding track. An eight-washing-needle assembly is arranged on the lifting needle support, four needles are liquid injecting needles and used for injecting washing liquid into a reaction cup, and other four needles are liquid sucking needles and used for sucking waste liquid in the reaction cup. The eight washing needles conduct washing liquid injection movement and waste liquid sucking movement on the reaction cup sequentially, and once diluting and three-time washing are conducted on magnetic beads in the reaction cup. An annular magnetic bead absorbing device is arranged below the inner side of the reaction cup rotation disc, and the plurality of mixing devices are arranged above two sides of the reaction cup rotation disc respectively. By means of the device, assembly line type washing of the magnetic beads is achieved, washing is thorough, magnetic bead loss is smaller, structure is optimized, control is simple, relatively independent functions are achieved, and the device is suitable for a whole automatic system.

Description

technical field [0001] The invention relates to a full-automatic chemiluminescence immune detection system or instrument, in particular to a magnetic bead cleaning device for a full-automatic chemiluminescence immune analyzer. Background technique [0002] Luminescence immunoassay is a new type of ultra-trace analysis technology established by combining luminescence analysis and immune reaction. This technology uses a chemical or bioluminescent system as an indicator system for antigen-antibody reactions to quantitatively detect antigens or antibodies. This method has both the high sensitivity of luminescence analysis and the high specificity of antigen-antibody reaction. Magnetic bead washing is not a reaction step in the CLIA process, but it is the key to the success of the experiment. The purpose of washing is to wash away the substances in the reaction solution that are not bound to the solid-phase antigen and antibody, as well as the interfering substances that are no...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B08B3/04B08B13/00
CPCB08B3/044B08B3/08B08B3/14
Inventor 不公告发明人
Owner BEIJING LEADMAN BIOCHEM
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