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Method for preparing pratia nummularia extract, extract and application thereof

A technology for extracting Herba japonica, applied in the field of preparation of Herba japonica extract, to achieve obvious liver protection effect and enhance SOD activity

Active Publication Date: 2014-02-19
广西中医药大学附属瑞康医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there has been no technology to prepare active extracts from C. chinensis, nor has there been any report on the application of drugs or health products to prevent and treat liver damage with C. sativa as the main component

Method used

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  • Method for preparing pratia nummularia extract, extract and application thereof
  • Method for preparing pratia nummularia extract, extract and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The anti-hepatic damage active extract of Tonghammer japonica, which is prepared by the following method:

[0023] (1) Take the dried scalloped grass, grind it into fine powder, 200 mesh, put it into the extraction tank, add 15 times the amount of 50% ethanol to extract 3 times, filter, combine the extracts, concentrate until no alcohol smell, Extraction A is obtained and set aside.

[0024] (2) Take the raw material slag filtered in step (1), heat and reflux with 10 times the amount of water to extract 3 times, filter, combine the extracts and concentrate to extract B, and set aside.

[0025] (3) Take the extracts A and B of steps (1) and (2), combine them, dry them in a vacuum, and pulverize them into fine powder to obtain the extract of Scallopedia chinensis.

Embodiment 2

[0027] The anti-hepatic damage active extract of Tonghammer japonica, which is prepared by the following method:

[0028] (1) Take the dried scalloped grass, grind it into fine powder, 180 mesh, put it into the extraction tank, add 15 times the amount of 90% ethanol to extract 3 times, filter, combine the extracts, concentrate until no alcohol smell, Extraction A is obtained and set aside.

[0029] (2) Take the raw material slag filtered in step (1), heat and reflux with 10 times the amount of water to extract 3 times, filter, combine the extracts and concentrate to extract B, and set aside.

[0030] (3) Take the extracts A and B of steps (1) and (2), combine them, dry them in a vacuum, and pulverize them into fine powder to obtain the extract of Scallopedia chinensis.

Embodiment 3

[0032] The anti-hepatic damage active extract of Tonghammer japonica, which is prepared by the following method:

[0033] (1) Take the dried scalloped grass, grind it into a fine powder, 200 mesh, put it into the extraction tank, add 15 times the amount of 1% ethanol to extract 3 times, filter, combine the extracts, concentrate until no alcohol smell, Extraction A is obtained and set aside.

[0034] (2) Take the raw material slag filtered in step (1), heat and reflux with 10 times the amount of water to extract 3 times, filter, combine the extracts and concentrate to extract B, and set aside.

[0035] (3) Take the extracts A and B of steps (1) and (2), combine them, dry them in a vacuum, and pulverize them into fine powder to obtain the extract of Scallopedia chinensis.

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PUM

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Abstract

The invention relates to a medicinal plant Pratia begonafolia (Wall) Lindl.or P.nummularia (Lam.) A.Br.et Aschers, and in particular relates to a method for preparing a pratia nummularia extract, an extract prepared by the method and application of the extract. On the research basis of the original chemical compositions and traditional efficacy of pratia nummularia, the active extract of pratia nummularia is prepared at the same time. Compared with the prior art, the pratia nummularia extract can significantly reduce ALT and AST activities in CC14 / alcohol-induced liver injury model mice serum and MDA content in a liver tissue and enhance the SOD activity of liver, and the active extract has an obvious a liver-protective effect on chemical liver injury and alcoholic liver injury.

Description

technical field [0001] The present invention relates to the medicinal plant Pratia begonafolia (Wall) Lindl.or P.nummularia (Lam.) A.Br.et Aschers], in particular to a preparation method of the extract of Pratia begonafolia (Wall) Lindl.or P.nummularia (Lam.) A.Br.et Aschers, and to prepare The extract obtained, and the use of the extract. Background technique [0002] Liver disease has always been one of the diseases that plague human health. Liver damage is the liver damage caused by the invasion of external factors. At present, according to the liver damage caused by different reasons, hepatitis can be divided into the following types: drug-induced hepatitis, alcoholic hepatitis and viral hepatitis. Liver damage caused by various harmful factors can manifest as liver necrosis, fatty liver, cholestasis, liver fibrosis, cirrhosis, etc., and eventually develop into liver cancer. [0003] As we all know, many Chinese herbal medicines have a certain protective effect on acut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/34A61P1/16
Inventor 赵立春
Owner 广西中医药大学附属瑞康医院
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