Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of a kind of clump extract in preparation of medicine for treating pulmonary tuberculosis

An extract and a technology for pulmonary tuberculosis, which is applied to the application field of the extract of Radix vulgaris in the preparation of medicines for treating pulmonary tuberculosis, can solve the problems such as no reports on the extract of Radix vulgaris, and achieve significant anti-tuberculosis effect, low production cost, and operation of the preparation process. easy effect

Inactive Publication Date: 2015-12-09
于淑娟
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The above-mentioned documents and patents, etc., have not yet seen the report that the extract of Conglia spp. is used to prepare drugs for the treatment of pulmonary tuberculosis.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of a kind of clump extract in preparation of medicine for treating pulmonary tuberculosis
  • Application of a kind of clump extract in preparation of medicine for treating pulmonary tuberculosis
  • Application of a kind of clump extract in preparation of medicine for treating pulmonary tuberculosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the preparation of Congfu extract

[0035] (1) Congfu 30kg, use 95% ethanol as solvent, heat and reflux extraction, extraction times are 3 times, each extraction time is 2 hours, each solvent dosage is 12 times the weight of Congfu, filter to obtain the medicine Slag A and extract, ethanol is recovered from the extract, concentrated, and dried to obtain the extract A of Congfussia;

[0036] (2) Use the dregs A obtained in step (1) with water as a solvent, heat and reflux for extraction, the number of extractions is 2 times, each extraction time is 2 hours, and the amount of solvent used each time is 12 times the weight of the cluster, filter and extract The solution is concentrated to a relative density of d=1.11, filtered to obtain the medicinal solution B;

[0037] (3) Pass the drug solution B obtained in step (2) through the D101 non-polar macroporous adsorption resin column, and first elute with water, and the water eluate directly passes through the ...

Embodiment 2

[0039] Embodiment 2: the preparation of Congfu extract

[0040](1) Congfu 23kg, use 80% ethanol as a solvent, extract by heating and reflux, the number of extractions is 1 time, each extraction time is 4 hours, and the amount of solvent used each time is 15 times the weight of Congfu, filtered to obtain the drug Slag A and extract, ethanol is recovered from the extract, concentrated, and dried to obtain the extract A of Congfussia;

[0041] (2) Use 10% ethanol as the solvent for the dregs A obtained in step (1), heat and reflux extraction, the number of extractions is 3 times, each extraction time is 1 hour, and the amount of solvent used each time is 8 times the weight of the cluster, Filtrate, recover ethanol from the extract, concentrate to a relative density of d=1.12, filter to obtain medicinal solution B;

[0042] (3) Pass the drug solution B obtained in step (2) through the AB-8 non-polar macroporous adsorption resin column, and first elute with water, and the water el...

Embodiment 3

[0044] Embodiment 3: the preparation of cloverleaf extract

[0045] (1) Congfu 24kg, use 100% ethanol as solvent, heat and reflux extraction, extraction times are 3 times, each extraction time is 1 hour, each time the amount of solvent is 8 times the weight of Congfu, filter to get medicinal residue A and the extract, the extract recovers ethanol, concentrates, and dries to obtain the extract A of Congfussia;

[0046] (2) The dregs A obtained in step (1) were extracted with 20% ethanol as a solvent by heating and reflux. The number of extractions was once, and the extraction time was 4 hours each time. Filtrate, recover ethanol from the extract, concentrate to a relative density of d=1.10, filter to obtain medicinal solution B;

[0047] (3) Pass the drug solution B obtained in step (2) through a D101 non-polar macroporous adsorption resin column, and first elute with water, and the water eluate directly passes through the X-5 polar macroporous resin column, and then use a con...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to new application of a Solms-Laubachia extract in preparation of drugs treating pulmonary tuberculosis. The Solms-Laubachia extract is prepared by: extracting Solms-Laubachia, and then performing macroporous adsorption resin purification twice to obtain a Solms-Laubachia extract A, a Solms-Laubachia extract B and a Solms-Laubachia extract C, and mixing the extracts in certain proportion, thus obtaining the Solms-Laubachia extract, which can be combined with a pharmaceutically acceptable carrier or other suitable excipients so as to be prepared into oral medication dosage forms according to conventional methods. The Solms-Laubachia extract can be used for preparation of drugs treating pulmonary tuberculosis.

Description

technical field [0001] The invention belongs to the field of biomedicine, and relates to the application of an extract of traditional Chinese medicinal materials in the preparation of medicines for treating tuberculosis, in particular to the application of the extracts of clumps of herbs in the preparation of medicines for treating tuberculosis. Background technique [0002] Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis invading the body under certain conditions. At present, the situation of global tuberculosis prevention and control is severe. In 2006, there were 9.2 million new tuberculosis cases in the world, and 1.7 million people died of tuberculosis in 2006. The treatment of pulmonary tuberculosis is mainly based on chemotherapy. In recent years, research on tuberculosis immunology has made great strides, enabling people to have a more comprehensive understanding of the onset, clinical course, prognosis and recurrence of tuberculosis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/31A61K9/20A61K9/16A61K9/48A61P31/06A61P11/00
Inventor 于淑娟
Owner 于淑娟
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com