Sample feeding device for measuring trace target substance

Abstract

The invention discloses a sample feeding device for measuring a trace target substance in blood sample. The sample feeding device comprises a detection channel, a sample feeding channel, an auxiliary channel, a detection pipeline unit, a sample feeding pipeline unit set, a detection pump, a sampling pump set and a control unit, wherein one section of the detection channel at the downstream is configured into a detection region and a detection window is arranged on the detection region; the sample feeding channel is connected with the upstream section of the detection channel to form a sample feeding bypath; the auxiliary channel is connected onto the detection channel between a connection point of the sample feeding channel and the detection region to form a sample feeding and leaking bypath; the detection pipeline unit is matched and connected with the detection channel and is provided with a control valve; the sample feeding pipeline unit set is matched and connected with the sample feeding channel and the auxiliary channel and is provided with a control valve set; the detection pump is connected into the upstream end of the detection channel by the detection pipeline unit and the corresponding control valve and is used for pumping a detection auxiliary solution; the sampling pump set is connected into the sample feeding channel by the sample feeding pipeline unit set and the corresponding control valve set and is used for correspondingly pumping a sample feeding liquid set; the control unit is connected with the detection pump, the sample feeding pump, the control valve and the control valve set and is used for logically controlling movement sequences of the detection pump, the sample feeding pump set and the matched control valve, and the control valve set.

Description

technical field [0001] The invention relates to a sampling device for trace target substances in blood samples, which belongs to the technical field of biomedicine. Background technique [0002] At present, the occurrence of human diseases often produces changes in the type or quantity of biomolecules in the body. People can detect early diagnosis of diseases or understand the evolution of diseases by detecting the changes in the production or quantity of some marker biomolecules in the body. For example, myoglobin, Mb, creatine kinase isoenzyme (Creatine Kinase MB, CK-MB) and cardiac troponin I (Cardiac Troponin I, cTnI) protein molecules in the blood will be produced and the concentration will increase when the heart is injured . Clinicians use the content of these biochemical markers in the body to diagnose the degree of heart damage or the effect of treatment. However, the content of specific marker molecules for most diseases is very low, and it is still a great chall...

AI Technical Summary

Problems solved by technology

[0007] At present, the routine detection methods of biochemical markers in blood include radioimmunoassay RIAs, high-pressure liquid chromatography, electrochemical analysis, protein analyzers, various diagnostic kits and immunochromatographic test strips, etc. These methods are ubiquitous. The shortcomings of radioactive contamination, the need for large instruments, time-consuming, and incapable of quantitative detection have certain limitations in clinical application.

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