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Traditional Chinese medicine composition for cerebral arterial thrombosis

A technology for ischemic stroke and composition, which is applied in the field of traditional Chinese medicine composition for ischemic stroke, can solve the problems of difficult quality control of medicines, unfavorable industrial production, and increased pain of patients, and achieve remarkable and reliable curative effect and high medicinal properties. Peaceful, low-cost results

Inactive Publication Date: 2014-02-05
吴鑫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, Chinese patents such as CN101474380 and CN101721572 also disclose some other traditional Chinese medicine compositions for the treatment of ischemic stroke, but their formulations are complicated, the production cost is high, and the quality control of medicines is difficult, which is not conducive to industrial production.
[0005] Traditional Chinese medicine prescriptions in the prior art lack dialectics, the treatment cycle is long, the symptoms are not strong, the curative effect is not obvious, and even bring side effects to patients, increase the pain of patients, and finding effective and safe medicines from natural medicines has become a clinical problem. Important direction of hemorrhagic stroke

Method used

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  • Traditional Chinese medicine composition for cerebral arterial thrombosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine composition for ischemic stroke, which is prepared from the following raw materials in parts by weight:

[0022] 30 parts of Rhodiola, 30 parts of Angelica, 25 parts of Acanthopanax senticosus, 25 parts of Scutellaria barbata, 25 parts of Cassia seeds,

[0023] 23 parts of Radix Scutellariae, 20 parts of Dilong, 20 parts of Gynostemma pentaphyllum, 20 parts of Trichosanthes, 20 parts of Chuanxiong,

[0024] 17 parts of Shichangpu, 17 parts of Caulis spatholobi, 15 parts of Astragalus, 15 parts of Perilla Leaf, 15 parts of Turmeric,

[0025] 12 parts of Muxiang, 10 parts of Mulberry, 10 parts of Epimedium, 10 parts of Plantago, 9 parts of Eupatorium,

[0026] 7 parts of Cistanche, 5 parts of Maqianzi, 5 parts of Chuanwu.

[0027] The preparation and administration method of the pharmaceutical composition of the present invention is as follows: take the above-mentioned weight parts of the raw material medicine (proportion unit: gram) and mix them unifo...

Embodiment 2

[0033] Zoological experiment

[0034] There are 30 healthy Kunming mice, half male and half male, and weighing 18.5±2.0g. The 30 mice are randomly divided into two groups, half male and half male. 10 of them are used as control group and irrigated with normal water; the other 20 mice Mice were given the drug of Example 1, and the acute toxicity experiment with mice showed that: Compared with the control group, there was no significant difference in mice after administration. The experiment was observed for two consecutive weeks. The mice's general condition, food intake, drinking water, and weight gain were all normal. On the day of administration and within two weeks after administration, no animal deaths were seen, indicating that the drug has low acute toxicity and is safe for clinical use.

[0035] Long-term toxicity test

[0036] Sixty SD rats were selected, half male and half male. According to body weight, they were randomly divided into 2 groups, namely the control group (...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for cerebral arterial thrombosis. The composition is prepared from the following raw materials in parts by weight: 30 parts of rhodiola rosea, 30 parts of angelica sinensis, 25 parts of acanthopanax root, 25 parts of sculellaria barbata, 25 parts of semen cassiae, 23 parts of semen raphani, 20 parts of lumbricus, 20 parts of gynostemma pentaphylla, 20 parts of radices trichosanthis, 20 parts of ligusticum wallichii, 17 parts of rhizoma acori graminei, 17 parts of caulis spatholobi, 15 parts of astragalus membranaceus, 15 parts of folia perillae acutae, 15 parts of radix curcumae, 12 parts of radix aucklandiae, 10 parts of mulberry, 10 parts of herba epimedii, 10 parts of semen plantaginis, 9 parts of hiraute shiny bugleweed herb, 7 parts of cistanche deserticola, 5 parts of nux vomica and 5 parts of radix aconiti preparata, wherein the raw materials are combined and complemented with each other. The composition has a rapid effect on the cerebral arterial thrombosis, thereby being wide in application prospect.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition using Chinese herbal medicine as a raw material for ischemic stroke. Background technique [0002] Stroke is a disorder of cerebral blood circulation that starts suddenly. Also called a cerebrovascular accident. Refers to patients with cerebrovascular diseases, caused by various predisposing factors that cause intracerebral artery stenosis, occlusion or rupture, resulting in acute cerebral blood circulation disorders, clinically manifested as symptoms and signs of transient or permanent brain dysfunction. It is an acute disease caused by a vascular disease that carries blood to the brain. Stroke can cause sudden damage to brain tissue, usually when the blood vessels that deliver oxygen and other nutrients to the brain burst, or when the blood vessels are blocked by blood clots or other particulate matter. If...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10A61K35/56A61K35/62
Inventor 吴鑫肖宁
Owner 吴鑫
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