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Aerosol used for treating traumatic injury and preparation method thereof

A technology for bruises and aerosols, applied in aerosol delivery, medical preparations containing active ingredients, anti-inflammatory agents, etc.

Active Publication Date: 2013-12-25
GUIZHOU JINQIAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, blood circulation promoting and blood stasis dispelling and dysmenorrhea relieving pain are the basic principles of bruise treatment based on soft tissue injury; Slow effect, complex preparation process, high cost, certain irritation and side effects, etc.

Method used

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  • Aerosol used for treating traumatic injury and preparation method thereof
  • Aerosol used for treating traumatic injury and preparation method thereof
  • Aerosol used for treating traumatic injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Liquid formula: Touguxiang 50g, red hemp 50g, dragon palm blood 40g, auspicious grass 50g, sorrel grass 40g, white dragon beard 30g, borneol 30g, camphor 40g, polyvinyl alcohol 18g, azone 10ml, propylene glycol 4ml , Liquid carbon dioxide 130ml.

[0050] Process: After crushing the six medicinal materials of Touguxiang, red hemp, Feilongzhangxue, auspicious grass, fermented sorrel, and white dragon's beard into the coarsest powder, reflux extraction with 8 times and 7 times the amount of 75% ethanol for 2 hours , 1.5h, filter, combine the extracts, recover ethanol under reduced pressure and concentrate it into a concentrated solution with a relative density of 1.20 at 40°C, let it cool, and set aside; the above concentrated solution is precision filtered, and camphor and borneol are added to the filtered concentrated solution Completely dissolve, then add polyvinyl alcohol, azone, propylene glycol, stir to dissolve, mix evenly, add 75% ethanol to 1000ml, divide into 100...

Embodiment 2

[0056] Liquid formula: Touguxiang 80g, red hemp 80g, Feilongzhangxue 70g, auspicious grass 80g, sorrel grass 70g, white dragon beard 50g, borneol 50g, camphor 70g, polyvinyl alcohol 20g, azone 12gml, propylene glycol 6ml , Liquid carbon dioxide 150ml.

[0057] Process: After crushing the six medicinal materials of Touguxiang, red hemp, Feilongzhangxue, auspicious grass, fermented sorrel and white dragon's beard into the coarsest powder, reflux extraction with 75% ethanol for 3 hours, filter, and recover the extract under reduced pressure Concentrate ethanol into a concentrated solution with a relative density of 1.20 at 40°C, let it cool, and set aside; the above-mentioned concentrated solution is finely filtered, and camphor and borneol are added to the filtered concentrated solution to dissolve completely, and then polyvinyl alcohol, azone, and propylene glycol are added Stir to dissolve, mix evenly, add 75% ethanol to 1000ml, pack according to 100ml per bottle, press 15ml o...

Embodiment 3

[0063] Liquid formula: 20g Touguxiang, 20g Red Hemp, 20g Feilongzhangxue, 20g Auspicious Grass, 10g Sorrel Grass, 10g White Dragon’s Beard, 10g Borneol, 20g Camphor, 15g Polyvinyl Alcohol, 8ml Azone, 2ml Propylene Glycol , Liquid carbon dioxide 100ml.

[0064] Process: After crushing the six medicinal materials of Touguxiang, Honghema, Feilongzhangxue, Auspicious Grass, Sorrelweed and Bailongxu into the coarsest powder, reflux extraction with 75% ethanol for 3 times, each time for 1h, filter, Combine the extracts, recover ethanol under reduced pressure, concentrate the concentrated solution with a relative density of 1.20 at 40°C, let it cool, and set aside; the above concentrated solution is precision filtered, and camphor and borneol are added to the filtered concentrated solution to dissolve completely, and then polyethylene Stir alcohol, azone, and propylene glycol to dissolve, mix well, add 75% ethanol to 1000ml, divide into 100ml bottles, press 10ml liquid carbon dioxide...

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Abstract

The invention discloses an aerosol used for treating traumatic injury and a preparation method thereof. The aerosol is prepared from Gaultheria yunnanensis, Laportea sinensis, Asiatic toddalia root, pink reineckea herb, creeping oxalis, longleaf luckyweed flower, borneol, camphor and accessories. The aerosol is capable of promoting blood circulation to remove blood stasis and relieving swelling and pain. According to the invention, pure Miao medicines are used as raw materials to prepare the aerosol, and the aerosol has the advantages of long action time, convenient usage, a good curative effect and easy storage; a film forming material is added, a propellent is employed to spray the aerosol onto an affected part to form a medicinal film, so external infection is avoided and the aerosol is a sustained release preparation and especially applicable to the majority of patients.

Description

technical field [0001] The invention relates to an aerosol for treating bruises and a preparation method thereof, belonging to the field of pharmaceutical technology. technical background [0002] With the effective and rapid development brought by the innovation and introduction of high-tech to the society, people's modern life is gradually developing towards fast-paced and diversified development. When people use modern public facilities and modern means of transportation, modern industrial and agricultural production, various sports activities and daily life, they often accidentally step on the air, twist, stumble, etc. This type of bruises, which are mainly acute and chronic soft tissue injuries, is a common disease and a high incidence in modern people's life. There are many pains, swelling, bleeding, fractures, dislocations, etc. in the wounds, and some internal organs are also injured. Life has had an extremely serious impact. There are many causes of bruises, and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/12A61P29/00A61K31/045A61K31/125
Inventor 张芝庭何莉华
Owner GUIZHOU JINQIAO PHARMA
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