A preparation method of Qingchang Granules used before induced labor in late pregnancy

Abstract

The invention discloses a preparation method of bowel clearing granules before late pregnancy labor induction, which aims to solve the problem of bowel clearing before late pregnancy labor induction. The invention is characterized by comprising the following active pharmaceutical ingredients in parts by weight: Horseweed herb, Fructus Cinnamomi, ternate buttercup root, Trachelospermum jasminoides, Asarum maximum Hemsl., rhizoma polygonati, fructus psoraleae, dried orange peel, sunflower, Turbo cornutus Solander, plant soot and magnesium sulfate. The preparation method comprises the following steps: (1) extracting volatile oils from fructus psoraleae, Fructus Cinnamomi and Asarum maximum Hemsl. coarse powders for later use; (2) pulverizing Turbo cornutus Solander and plant soot into fine powders for later use; (3) decocting horseweed herb, ternate buttercup root, Trachelospermum jasminoides, rhizoma polygonati, sunflower and dried orange peel with water 2 times, filtering, merging the filtrates, concentrating the filtrate, adding ethanol to precipitate, taking the supernatant, recovering the ethanol, and concentrating to obtain a thick paste; and (4) adding the volatile oils obtained in the step 1, the fine powders obtained in the step 2, and magnesium sulfate into the thick paste obtained in the step 3, stirring uniformly, granulating, and drying. The clinical experiment proves that the invention has the characteristic of favorable bowel clearing effect before late pregnancy labor induction, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a method for preparing intestinal-clearing granules used before induced labor in late pregnancy. Background technique [0002] Intestinal preparation before induction of labor in late pregnancy includes stimulating intestinal peristalsis, softening and clearing feces, eliminating intestinal gas, and preventing patients from increasing the chance of contamination due to anal sphincter relaxation after anesthesia that cannot control defecation; at the same time, reducing intestinal gas filling and the presence of feces affect the operation. Clinical practice has proved that oral cleansing of the mixed water decoction of rhubarb, Glauber's salt, and licorice can also reduce abdominal distension and discomfort after surgery. The traditional method is to take a residue-free liquid diet one day before the operation, take a laxative (such as: mannitol) orally in the evening before the operatio...

AI Technical Summary

Problems solved by technology

This intestinal preparation method has the following defects: ①Mannitol is a hypertonic dehydrating agent, which strongly stimulates the intestinal tract and has a significant impact on the operator’s mood and sleep state; ②The last enema time of the traditional method is 6 am in the morning of the operation Entering the operating room at 8 am, during which there is not enough time for the intestinal tract to be completely emptied, and it is easy to cause pollution during the operation; ③It does not have a beneficial effect on postoperative recovery

[0003] At present, it is also reported that traditional Chinese medicine preparations are used for preoperative bowel cleansing, such as oral administration of the above-mentioned rhubarb, mirabilite, and licorice mixed water decoction. The patient's mood and sleep state are significantly affected, and laxatives such as Boziren are not easy to control the time of laxative

Therefore, there is currently a lack of a drug that is suitable for preoperative bowel cleansing, effective catharsis and does not affect sleep, and can have a beneficial effect on postoperative recovery.