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Natural pharmaceutical extractive, and preparation method thereof

A technology of natural medicines and extracts, used in drug combinations, pharmaceutical formulations, antitumor drugs, etc.

Inactive Publication Date: 2013-10-16
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical extractive, and preparation method thereof

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Experimental program
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Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of Phellodendron radish seed decoction concentrated extract

[0033] According to the compatibility ratio of 1-4:1, take Cortex Phellodendron and Radish Seed, soak in distilled water, heat and decoct, filter with silk cloth, add distilled water to the medicinal residue, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate, Ultrafiltration membrane filtration, drying under reduced pressure, that is.

[0034] (2) Preparation of Phellodendron Phellodendri Ethyl Acetate Extract

[0035] Phellodendron cortex is crushed, soaked in 95% alcohol for 3 times, combined with ethanol extract, brown extract obtained by distillation under reduced pressure, dispersed in water, extracted with water, diethyl ether and ethyl acetate in sequence, part of ethyl acetate is distilled under reduced pressure, and dried to obtain phellodendron acetic acid ethyl ester extract.

[0036] (3) ...

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Abstract

The invention relates to a natural pharmaceutical extractive, and a preparation method thereof. The natural pharmaceutical extractive comprises concentrated extractive of water decocted radish seed, extractive of cortex phellodendri-vinegar naphtha, and sulforaphane according to the proportion of (6-9) : (3-6) : (3-5). The natural pharmaceutical extractive has an excellent curative effect on diarrhea related to cancer chemo-treatment and a synergistic effect on cancer chemo-treatment.

Description

technical field [0001] The present invention relates to a kind of natural medicine extract, more specifically relate to a kind of natural medicine extract that is made up of Phellodendron Phellodendron Radix Seed Water Decoction Concentrated Extract, Phellodendron Phellodendron Ethyl Acetate Extract and Radix Seedling, the preparation of this natural medicine extract The method and the use of the natural medicine extract in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is al...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P1/12A61P35/00A61K31/26
Inventor 石强
Owner 石强
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