Pedunculoside extraction method adopting holly as raw material

A technology of pedicel glucoside and extraction method, which is applied in the extraction and production of traditional Chinese medicine and in the field of medicine, which can solve the problems of difficult control of industrialization, high production components, and low efficiency, and achieve the effects of easy instantaneous control, uniform extraction, and increased efficiency

Active Publication Date: 2013-09-11
安徽世茂中药股份有限公司
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the process of extraction, there will be changes in properties, low efficiency, low purity, high production components, and industrialization is difficult to control.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Soak 500g of Sijiqing raw material in 2.5 liters of 60% ethanol solution for 0.5 hours, reflux extraction under 400W microwave at 10°C for 10 minutes, separate and obtain the extract, concentrate to obtain pedicel extract; Dissolve the extract with 0.5 liter of 70% ethanol solution, filter through 100 mesh activated carbon, collect the filtrate, adjust the solution to PH=6 with 0.05mol / L hydrochloric acid solution, add NaCl to make it saturated, cool to -4°C to precipitate, and collect by filtration Precipitated and dried to obtain 2.3 g of high-purity catechin glucoside with a purity of 95.1%.

Embodiment 2

[0014] Soak 500g of Sijiqing raw material in 5 liters of 75% ethanol solution for 3 hours, reflux extraction under 3500W microwave at 20°C for 30 minutes, separate and obtain the extract, and concentrate to obtain pelicin extract; Dissolve the extract in 0.8 liters of 60% ethanol solution, filter through 100 mesh activated carbon, collect the filtrate, adjust the pH of the solution to 7 with 0.2mol / L hydrochloric acid solution, add NaCl to make it saturated, cool to 10°C to precipitate, and collect the precipitate by filtration , dried to obtain 2.2 g of high-purity catechin glucoside, with a purity of 95.7%.

Embodiment 3

[0016] Soak 500g of Sijiqing raw material in 4 liters of 70% ethanol solution for 2.5 hours, reflux extraction in 3000W microwave at 20°C for 20 minutes, separate and obtain the extract, concentrate to obtain pelicin extract; Dissolve the extract with 0.9 liter of 65% ethanol solution, filter through 100 mesh activated carbon, collect the filtrate, adjust the solution to PH=6 with 0.1mol / L hydrochloric acid solution, add NaCl to make it saturated, cool to 0°C to precipitate, and collect the precipitate by filtration , dried to obtain 2.5 g of high-purity catechin glucoside, with a purity of 96.5%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A pedunculoside extraction method adopting holly as raw material includes steps of extraction and purification. The extraction step includes performing refluxed extracting and isolating on the holly raw materials, water and ethanol solution under condition of microwave at low temperature ranging from 10 DEG C to 20 DEG C to obtain extracting liquid, and concentrating to obtain pedunculoside extract; dissolving the pedunculoside extract by 70-75% ethanol, filtering through activated carbon with 100 meshes, collecting filtrate and adjusting solution PH to be equal to 6 to 7, adding NaCl to saturate, cooling to minus 4 DEG C to 10 DEG C to precipitate, filtering and collecting precipitate, and drying to obtain high-purity pedunculoside.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for extracting pelican glucoside from Sijiqing as a raw material, and belongs to the technical field of extraction and production of traditional Chinese medicines. Background technique [0002] Sijiqing is a plant belonging to the holly family. Distributed in various places south of the Yangtze River in my country, often growing in sparse forests. Its roots and leaves can be used as medicine, and its main effects are clearing away heat and detoxification; It is clinically used to treat cold and fever, cough due to lung heat, sore throat, urination, dysentery and diarrhea. [0003] Pelicin glucoside is one of the main active ingredients in Sijiqing, which belongs to glycosides. In recent years, domestic and foreign scholars have made some progress in the field of extraction of pedicel glycosides. For example, the Chinese patent (CN102649805) discloses a method for pr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07J63/00
Inventor 陈刚高波
Owner 安徽世茂中药股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap