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Methods and apparatuses for predicting the effects of erythropoesis stimulating agents (esa), and for determining a dose to be administered

A stimulant and action technology, applied in the field of prediction and device of the effect of hematopoietic stimulator (ESA) and the determination and device of the dosage, which can solve the problem of consuming large clinical medical resources

Active Publication Date: 2013-08-28
FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] From a practical point of view, the continuous monitoring of hemoglobin levels in the blood and the adjustment of the dose of erythropoiesis-stimulating hormone require a lot of clinical medical resources

Method used

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  • Methods and apparatuses for predicting the effects of erythropoesis stimulating agents (esa), and for determining a dose to be administered
  • Methods and apparatuses for predicting the effects of erythropoesis stimulating agents (esa), and for determining a dose to be administered
  • Methods and apparatuses for predicting the effects of erythropoesis stimulating agents (esa), and for determining a dose to be administered

Examples

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Embodiment Construction

[0105] Other aspects, features and advantages of the present invention can be clearly understood from the following description, drawings and claims. However, it must be understood that the present invention is not limited to the examples described.

[0106] figure 1 A device 9 is shown comprising a controller 11 for carrying out the method according to the invention. The device 9 is connected with an external database 13, which includes various measurement results and data required by the method of the present invention. The database 13 can also be an internal device. The means 9 may optionally include means 14 for inputting data into the controller 11 or the input means 9 . Such data can be information about the mass, volume, and concentration of hemoglobin (Hb), as described above. The data input to the device 9 may additionally include or replace information about the patient's hyperhydration or similar information. The results of the predictions, evaluations, calcula...

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Abstract

The present invention relates to a method for predicting the concentration or the mass of haemoglobin or an approximation thereof, respectively, in a body fluid and / or an extracorporeal sample thereof of a patient at a later, second point of time, the patient having theoretically or in reality been administered a certain dose of an erythropoesis stimulating agent at an earlier, first point of time. It relates further to a method for determining the dose of an erythropoesis stimulating agent to be administered to a patient, to a method for determining whether a patient is affected by circumstances leading to the loss of haemoglobin, to corresponding devices and to an erythropoesis stimulating medicament for use in the treatment of anemia. Finally the present invention relates to corresponding means, digital storage means, a computer program product, and a computer program.

Description

technical field [0001] The present invention relates to a method as claimed in the preamble of claim 1 and / or as claimed in claim 19 and / or claim 33, which is used to predict or evaluate the patient's body fluids at a later second time point. And / or the concentration or mass of hemoglobin in an in vitro sample or its approximate value, and the patient has theoretically or actually been administered a certain dose of a hematopoietic stimulator at an earlier first time point. The present invention further relates to a method as claimed in the preamble of claim 7 and / or as claimed in claims 29, 36 and / or 39 for determining the dose of a hematopoietic stimulator to be administered to a patient; The method requested in Item 13 is a method for determining whether a patient is affected by a condition that causes hemoglobin depletion; various corresponding devices, and an erythropoiesis-stimulating agent for treating anemia. Finally, the present invention relates to a digital storage...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/49G01N33/72
CPCA61P7/06G01N33/721G01N33/726G01N2800/52
Inventor 保罗·钱慕尼乌尔里克·摩怡希尔彼得·瓦贝尔塞巴斯蒂安·伟伊斯寇顿沃尔克·尼尔
Owner FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
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