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Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source

A source and group technology, applied in the direction of biochemical equipment and methods, microbial determination/inspection, etc.

Active Publication Date: 2014-07-02
INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no research on Chinese Han, Tibetan, and Uyghur populations

Method used

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  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source
  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source
  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] 135 individual test samples (one for each individual) used in embodiment 3 are from the specific sources of Han nationality, Tibetan nationality and Uighur nationality:

Embodiment 2

[0070] type source Quantity (parts) serial number

Embodiment 3

[0071] Han DNA samples Cases in this laboratory 12 1-12 Han nationality venous blood volunteer 33 13-45 Uighur blood spot samples Bingtuan Public Security Bureau 12 46-57 Uighur blood volunteer 33 58-90 Tibetan blood spot samples Cases in this laboratory 12 91-102 Tibetan blood volunteer 33 103-135

[0072] Among them, 12 Uighur blood spot samples were provided by Xinjiang Corps Public Security Bureau, 12 Tibetan blood spot samples and 12 Han blood spot samples were provided by the Physical Evidence Identification Center of the Ministry of Public Security.

[0073] Genomic DNA from venous blood was selected from Qiagen DNA Blood Midi Kit was extracted; blood spot samples were extracted with Qiagen’s DNA Mini M48 DNA Extraction Kit to extract DNA;

[0074] The methods used are conventional methods unless otherwise specified, and the reagent consumables and instruments used are listed in the table below:

[0075]...

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PUM

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Abstract

The present invention provides a method and system for inferring the source of the Han, Tibetan and Uyghur populations of individuals of unknown origin. The method includes: obtaining the genotypes of 94 specific loci of Han, Tibetan, and Uyghur populations by detecting the DNA of individuals of unknown origin; genotype frequency; multiply the genotype frequency of each specific locus to obtain the matching probability values ​​of the 94 specific loci in the Chinese, Tibetan, and Uighur populations; the population with the highest matching probability value is the individual of unknown origin source groups. The scheme of the present invention can realize the inference of the source of the Han, Tibetan and Uighur groups with high accuracy.

Description

technical field [0001] The present invention relates to a method and a system for inferring the origin of an individual of unknown origin, in particular to a method and a system for inferring the origin of an individual of unknown origin in Han, Tibetan, and Uighur groups. Background technique [0002] With the continuous improvement of the scientific, objectivity and accuracy requirements of judicial litigation activities, the field of physical evidence identification continues to develop, requiring more accurate analysis methods to determine the individual source of inspection materials in cases, DNA analysis Because of its accurate test results, it has become an important technical means in the field of physical evidence identification. [0003] Current forensic DNA analysis usually involves autosomal or Y chromosome tandem repeat (STR) detection, or mitochondrial sequencing and analysis of on-site biological evidence, such as blood, hair, cigarette butts, and semen spot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/68
Inventor 李彩霞魏以梁胡兰季安全贾竟李万水
Owner INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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