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Use of arctigenin in the preparation of medicines for treating or preventing glioma

A technology for arctigenin and glioma, which is applied in the field of medicine, can solve the problems of not publicizing the therapeutic effect of arctigenin on brain glioma, and achieves low incidence of adverse reactions, definite curative effect, and reduced tumor volume. and tumor index

Active Publication Date: 2016-03-02
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Arctigenin has significant antibacterial, antiviral, antitumor, and anti-PAF receptor effects, but the prior art does not disclose whether arctigenin has a therapeutic effect on brain glioma

Method used

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  • Use of arctigenin in the preparation of medicines for treating or preventing glioma
  • Use of arctigenin in the preparation of medicines for treating or preventing glioma
  • Use of arctigenin in the preparation of medicines for treating or preventing glioma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Arctium Aglycone Injection

[0018]

[0019] The preparation process: mix the prescription amount of propylene glycol and ethanol uniformly, add arctigenin, stir to dissolve, add the prescription amount of 0.9% sodium chloride solution, stir evenly, add 0.5% injection activated carbon, stir, and decarbonize to obtain.

Embodiment 2

[0020] Example 2 Arctium lappa aglycone injection

[0021]

[0022] Preparation process: add the prescription amount of PEG-400, add arctigenin, stir to dissolve, add 0.9% sodium chloride solution to 10ml, stir evenly, add 0.5% activated carbon for injection, stir, and decarbonize to get.

Embodiment 3

[0023] Example 3 Arctium lappa aglycone injection

[0024]

[0025] Preparation process: mix the prescription amount of ethanol and Tween-80 uniformly, add arctigenin, stir to dissolve, add water for injection to 10ml, stir evenly, add 0.5% activated carbon for injection, stir, and decarbonize to get.

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Abstract

The invention belongs to the field of medicine, and relates to medical application of arctigenin, in particular to application of the arctigenin in preparation of medicine for curing or preventing brain glioma. Preferably, the arctigenin is made into injection preparation. The dosage of the arctigenin for people is 0.1 mg / kg / day - 10 mg / kg / day. The arctigenin has the advantages of being precise in curative effect and low in toxic and side effect when used for curing or preventing brain glioma. Furthermore, the arctigenin enables clinical medication selection of a doctor to be further increased. Therefore, the arctigenin has a broad application prospect.

Description

Technical field [0001] The invention belongs to the field of medicine, and relates to a medical use of arctigenin, in particular to the application of arctigenin in the preparation and treatment of glioma. Background technique [0002] Tumor is one of the common diseases threatening human health, second only to cardiovascular disease. The research on tumor has made great progress. At present, a variety of radiotherapy and chemotherapy methods have been developed to treat tumors, but various drugs and therapies still exist Limitations, it is difficult to achieve a radical cure, and it is prone to drug resistance and side effects. Tumor mortality ranks first among various diseases. Data show that in 2006, 3 million people died of cancer in my country, and the incidence of tumors is still on the rise. Therefore, research on new and effective therapeutic drugs is still the main direction of current tumor treatment. [0003] Glioma is a tumor that occurs in the neuroectoderm, so it is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/365A61P35/00A61P35/04
Inventor 赵志全王潞王洪臣李涛
Owner LUNAN PHARMA GROUP CORPORATION
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