Alchemilla vulgaris extract as well as preparation method and application thereof in resisting wrinkle and whitening

A technology of kaleba extract, kaleba, which is applied in the field of chemistry, and can solve problems such as dependence on the body, damage, and harmfulness to the human body

Inactive Publication Date: 2013-06-05
SHANGHAI KELIKE BIOLOGICAL MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the anti-wrinkle cosmetics currently on the market are artificially designed. Although the effect is good, they often contain a variety of heavy metals, hormones and other ingredients that are harmful to the human body. Long-term use will cause dependence and damage to the body.

Method used

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  • Alchemilla vulgaris extract as well as preparation method and application thereof in resisting wrinkle and whitening
  • Alchemilla vulgaris extract as well as preparation method and application thereof in resisting wrinkle and whitening
  • Alchemilla vulgaris extract as well as preparation method and application thereof in resisting wrinkle and whitening

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 Kalewort extract

[0028] Take 10 kg of Cottonina basilica, pulverize it, and use 50 L of 90% ethanol aqueous solution to reflux extract 3 times, each time for 3 hours, to obtain 100 L of extract. The extract was concentrated under reduced pressure into an extract (concentration ratio 1:1.2, 60°C) and suspended in water. Then pass through a non-polar macroporous adsorption resin for decolorization, elute with water-ethanol (90:10) to obtain a lighter-colored solution of the extract of Kalejas, concentrate under reduced pressure, and evaporate the solvent to obtain the extract of Kassia.

Embodiment 2

[0029] The preparation of embodiment 2 Kalewort extract

[0030] Take 10 kg of Cottonina basilica, grind it, and extract it with 50 L of 75% ethanol aqueous solution for 3 times under reflux, each time for 3 hours, to obtain 100 L of extract. The extract was concentrated under reduced pressure into an extract (concentration ratio 1:1.3, 60°C) and suspended in water. Then pass through a non-polar macroporous adsorption resin for decolorization, elute with water-ethanol (90:10) to obtain a lighter-colored solution of the extract of Kalejas, concentrate under reduced pressure, and evaporate the solvent to obtain the extract of Kassia.

Embodiment 3

[0031] The preparation of embodiment 3 Kalewort extract

[0032] Take 10kg of Cottonina basilica, pulverize it, and use 50L of 95% ethanol aqueous solution to reflux extract 3 times, each time for 3 hours, to obtain 100L of extract. The extract was concentrated under reduced pressure into an extract (concentration ratio 1:1.1, 60°C) and suspended in water. Then decolorize through polar, medium polar or non-polar macroporous adsorption resin, and elute with water-ethanol (90:10) to obtain a lighter-colored kaleba extract solution, which is concentrated under reduced pressure and evaporated to dryness. That is the extract of kale.

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Abstract

The invention relates to the chemical field, and in particular relates to an alchemilla vulgaris extract as well as a preparation method and an application thereof in resisting wrinkle and whitening. The alchemilla vulgaris, prepared by the method through organic reagent extraction and macroporous absorption resin purification, can effectively remove pigment and other colored components in the extract, to obtain comparatively light extract, so that the preparation method is applicable to preparation of cosmetics. The prepared extract or cosmetic, through an anti-wrinkle test, a moisturizing test, a skin color test and a fibroblast cell propagation activity test, has effects on resisting wrinkle and whitening.

Description

technical field [0001] The invention relates to the field of chemistry, in particular to an extract of kalebasin, its preparation method and its anti-wrinkle and whitening application. Background technique [0002] Skin aging is a phenomenon of skin aging caused by natural or unnatural factors. After birth, the skin tissue becomes more and more developed, and its functions are gradually active. When it reaches a certain age, it will begin to degenerate. This degeneration often proceeds slowly without people's awareness. It is a continuous and gradual physiological process that directly affects the skin. Appearance and function. [0003] The phenomenon of skin aging is mainly manifested in two aspects: one is the low physiological function. The function of sebaceous glands and sweat glands declines, the excretion of sweat and sebum decreases, and the skin gradually loses its luster and becomes dry. The blood circulation function is decreased to supplement the necessary nut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02A61Q19/08A61K8/9789
Inventor 张寿德赵华燕姜鹏
Owner SHANGHAI KELIKE BIOLOGICAL MEDICAL TECH
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