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YouguiWan application

A technique of Yougui Pill and application, applied in the application field of Yougui Pill in improving chronic liver injury medicine

Inactive Publication Date: 2013-05-01
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no report that Yougui Pills can improve liver function

Method used

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  • YouguiWan application
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0012] 1. Purpose of the experiment: To observe the effect of Yougui Pill on chronic liver injury

[0013] 2. Experimental materials

[0014] 2.1 Drugs

[0015] Yougui pills: 240 grams of Rehmannia glutinosa, 60 grams of aconite (Paofu tablets), 60 grams of cinnamon, 120 grams of Chinese yam, 90 grams of dogwood (wine-roasted), 120 grams of dodder, 120 grams of antler gum, 120 grams of medlar, 90 grams of angelica, Eucommia (fried with salt) 120 grams.

[0016] The decoction pieces of Chinese medicine were purchased from Shanghai Huayu Pharmaceutical Co., Ltd., and the extract was prepared by the Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine. The method is as follows: decoction twice, the first water consumption is 10 times the amount of the drug, and the second time is 8 times the drug 1 hour at a time from boiling, decoct twice and decoct and concentrate to the required temperature, store at -20°C, and incubate at 37°C before gava...

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Abstract

The invention discloses an application of YouguiWan, and specifically discloses an application of YouguiWan in preparing medicines used for ameliorating chronic liver injury. With YouguiWan, CCl4 mouse serum ALT level can be reduced, liver tissue collagen area can be reduced, and liver tissue Hyp content can be reduced. Also, with YouguiWan, DMN rat liver tissue collagen area can be reduced, liver tissue Hyp content can be reduced, and rat weight can be increased.

Description

technical field [0001] The invention relates to an application of Yougui Pills, in particular to the application of Yougui Pills in medicines for improving chronic liver damage, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Recurrent chronic liver injury is a relatively common liver injury in clinical practice. Chronic liver injury caused by various etiologies can cause inflammation and necrosis of liver cells, and secondary liver fibrosis. Hepatic fibrosis refers to liver fibrosis. Excessive tissue deposition, the result of an imbalance between fibroproliferation and fibrolysis. If liver fibrosis is not effectively controlled, it may eventually develop into liver cirrhosis and cause serious complications (portal hypertension, liver failure, liver cancer, etc.). Therefore, protecting liver cells and reducing various damage factors can prevent or delay the progress of liver fibrosis and its complications. [0003] After l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P1/16A61K35/32
Inventor 王晓玲闫晓风叶目亭杰刘平
Owner SHANGHAI UNIV OF T C M
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